Evidence map›Paper›PMID 41982152›Full record

ArticleNutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition2026

Single-center experience of the Crohn's disease exclusion diet in the United States: A retrospective study.

Mayah Greenfield, Caroline Salozzo, Wenya Chen, Jennifer Strople, Jeffrey Brown, Joseph Runde

Abstract read
In one paragraph

Article in Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mayah GreenfieldRobert Louis Katz & Manne Research Institute Summer Scholars Program, Northwestern Medicine, Chicago, Illinois, USA.
Caroline SalozzoDepartment of Clinical Nutrition, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Wenya ChenStanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Jennifer StropleDivision of Gastroenterology, Hepatology & Nutrition, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Jeffrey BrownDivision of Gastroenterology, Hepatology & Nutrition, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Joseph RundeDivision of Gastroenterology, Hepatology & Nutrition, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0001-5556-0660

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Crohn's Disease Exclusion Diet (CDED) offers a dietary means of inducing and maintaining remission for patients with Crohn's disease (CD). Descriptions of efficacy have emerged primarily from Israel, Europe, and Canada. Here, we offer real-world experience, from a tertiary care center in the United States.

methodsWe conducted a retrospective chart review of patients receiving education on the CDED and those adopting the diet. Demographics, medication exposure, disease-related complications, and reported side effects were collected. Corticosteroid-free clinical remission (SF-CR) was measured at weeks 6, 12, and 24 via the pediatric Crohn's Disease Activity Index (PCDAI). Biomarkers were collected at baseline and while on the diet.

resultsOnly 8% (n = 32) of children with CD had met with a dietitian regarding the CDED. Of those, 75% (n = 24) adopted the diet. A statistically significant change in PCDAI from baseline to weeks 6, 12, and 24 (χ

conclusionIn this single-center experience of children with mild to moderate CD who adopted the CDED, adherence was a challenge. However, for those who were able to sustain the diet, the CDED offered a safe and effective means of clinical remission.

Indexed as

Crohn DiseaseAdolescentBiomarkersChildElimination DietsFecesFemaleHumansLeukocyte L1 Antigen ComplexMaleRemission InductionRetrospective StudiesSeverity of Illness IndexTreatment OutcomeUnited StatesBiomarkersLeukocyte L1 Antigen ComplexCrohn's diseaseCrohn's disease exclusion diet, dietary therapypediatrics

Identifiers

PMID41982152
PMCPMC13421003

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.