Evidence map›Paper›PMID 41983167›Full record

ReviewRSC advances2026

Benzimidazole motifs in drug discovery: sustainable synthetic strategies and emerging biological applications.

Glanish Jude Martis, Santosh L Gaonkar

Abstract readReview
In one paragraph

Review in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Glanish Jude MartisManipal Institute of Technology, Manipal Academy of Higher Education Manipal 576104 Karnataka India sl.gaonkar@manipal.edu.
Santosh L GaonkarManipal Institute of Technology, Manipal Academy of Higher Education Manipal 576104 Karnataka India sl.gaonkar@manipal.edu.ORCID https://orcid.org/0000-0003-2687-6927

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Benzimidazole compounds have laid a strong foundation both in the domains of synthetic organic chemistry and in biological advances. The green synthesis of these materials, which favour sustainability with respect to nature is highly important. Photocatalysis, microwave-assisted and ultrasound-assisted synthesis of benzimidazoles have numerous advantages over conventional methods of synthesis. Various modes of synthesis and catalysis have been developed to take benzimidazole chemistry to different levels, producing attractive compounds in high yields and lowering the formation of impurities. Apart from their synthetic protocols, benzimidazoles have shown great performance in their biological actions in antimicrobial, anticancer, anti-inflammatory and antimycobacterial evaluations. Therefore, we here discuss recent progress in the green synthetic methods of benzimidazoles with their advances in producing biologically active compounds - possibly future potential drug candidates!

Identifiers

PMID41983167
PMCPMC13071802

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.