ArticleFEBS open bio2026
RETRACTION: Downregulation of SUMO2 inhibits hepatocellular carcinoma cell proliferation, migration and invasion.
Article in FEBS open bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Retraction of
Authors and funding
0 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
retractionJ. Chen, C. Chen, Y. Lin, Y. Su, X. Yu, Y. Jiang, Z. Chen, SY. Ke, SZ. Lin, L. Chen, Z. Zhang, and T. Zhang, "Downregulation of SUMO2 inhibits hepatocellular carcinoma cell proliferation, migration and invasion," FEBS Open Bio 11, no. 6 (2021): 1771-1784. https://doi.org/10.1002/2211-5463.13173. The above article, published online on 14 May 2021 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Miguel De la Rosa; the Federation of European Biochemical Societies; and John Wiley & Sons Ltd. A third party reported that images in the Bel-7404 cell migration assay in Figure 5A contained overlapping duplicated sections and that the SMMC-7721 cell invasion assay in Figure 5C also contained overlapping duplicated sections. Further investigation by the editors and the publisher found additional overlapping duplicated sections in the SMMC-7721 cell migration assay images in Figure 5A and potential duplication of a portion of the GAPDH band between the Bel-7404 image in Figure 4B and Bel-7404 image in Figure 5F. The authors responded to an inquiry by the publisher. However, the editors found that the explanation and raw data provided by the authors did not adequately address the concerns. The evidence of image overlap and duplication in several figures has compromised the editor's confidence in the conclusions presented in the manuscript. As a result, the Editor-in-Chief, FEBS Press, and John Wiley and Sons Ltd. have determined that a retraction is necessary. The authors were informed about the retraction.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.