Evidence map›Paper›PMID 41985165›Full record

ArticleJournal of the American Chemical Society2026

Designer Aromatic Cations for Photoinduced Protein Ligation, Imaging, and Intracellular Labeling at Extended Wavelengths.

Pranab C Saha, Pooja R Solanke, Sanwayee Biswas, Vishal Agarwal, Michael T Taylor

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Pranab C SahaDepartment of Chemistry & Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.
Pooja R SolankeDepartment of Chemistry & Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.
Sanwayee BiswasDepartment of Chemistry & Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.
Vishal AgarwalDepartment of Chemistry & Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.
Michael T TaylorDepartment of Chemistry & Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.

Funding

New Chemical Tools for Optically Controlled Protein ModificationR35GM143120 · NIGMS · UNIVERSITY OF WYOMING · PI TAYLOR, MICHAEL T · 2021 to 2025
$1.6M
NIGMS NIH HHS R35 GM143120
6 · The paper itself

Abstract

Photoinduced protein labeling strategies have become essential tools in chemical biology, but most strategies require high-energy wavelengths of light as input to drive reactivity. Recently, we reported a biocompatible method for engaging photoinduced electron transfer to drive protein labeling using biarylpyridinium salts, and here, we report the design of a series of aromatic cation salts that trigger this process using longer wavelengths of light while maintaining a sterically minimal profile. We achieved this through the systematic study of structure-reactivity relationships of various donor-acceptor pyridinium salts possessing extended conjugation, and these studies revealed the need of a constrained

Indexed as

Fluorescent DyesProteinsCationsGreen LightHumansMolecular StructurePhotochemical ProcessesCationsFluorescent DyesProteins

Identifiers

PMID41985165
PMCPMC13215081

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.