Evidence map›Paper›PMID 41985395›Full record

ArticleInternational dental journal2026

Divergent Patient-Reported Outcomes to Periodontal Therapy: A Prospective Study of Gingivitis Subtypes.

Guifen Cao, Xuan Ying, Xiaojun Li, Yue Dai, Yanli Huang, Guannan Bai, Xia Cai

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PubMed Full text at PMC Publisher
In one paragraph

Article in International dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guifen CaoDepartment of Periodontology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, Zhejiang, China.
Xuan YingDepartment of Periodontology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, Zhejiang, China.
Xiaojun LiDepartment of Periodontology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, Zhejiang, China.
Yue DaiDepartment of Periodontology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, Zhejiang, China.
Yanli HuangDepartment of Periodontology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, Zhejiang, China.
Guannan BaiDepartment of Child Health Care, Children's Hospital, National Clinical Research Center for Child Health, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Electronic address: guannanbai@zju.edu.cn.
Xia CaiDepartment of Periodontology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, Zhejiang, China. Electronic address: cxshidou@zju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION AND

aimsSubtype-specific differences in patient-reported outcomes (PROs) following periodontal therapy for gingivitis remain poorly defined. This study compared changes over time in clinical parameters, oral health-related quality of life (OHRQoL), and dental anxiety (DA) following periodontal therapy among individuals with localized gingivitis (LG), generalized gingivitis (GG), and periodontally healthy controls (PH). MATERIALS AND

methodsNinety participants (30 per group) underwent scaling, polishing, and oral hygiene instruction. Clinical parameters (bleeding on probing [BOP], gingival index [GI], plaque index [PLI]) and patient-reported outcomes (Oral Health Impact Profile-14 [OHIP-14] and Corah's Dental Anxiety Scale [C-DAS]) were recorded at baseline (t0), 1 month (t1), and upon achieving periodontal health (t2; BOP < 10%).

resultsAll groups showed significant improvements in GI and PLI (P < .05). BOP decreased significantly in LG and GG (both P < .05), but not in PH. PROs exhibited distinct, subtype-specific patterns: OHRQoL (OHIP-14) improved significantly in GG only at t2 (P < .05), whereas the LG improved at both t1 and t2 (all P < .05). In addition, dental anxiety (C-DAS) decreased significantly in the GG at both t1 and t2 (P < .05).

conclusionPeriodontal therapy provides dual clinical and psychological benefits, with the pattern of improvement in OHRQoL and reduction in dental anxiety contingent on gingivitis subtype. The registration number: ChiCTR2300076378.

Indexed as

GingivitisPatient Reported Outcome MeasuresAdultDental AnxietyDental Plaque IndexDental ScalingFemaleHumansMaleMiddle AgedOral HealthOral HygienePeriodontal IndexProspective StudiesQuality of LifeDental anxietyGingivitisOral health-related quality of lifePeriodontal healthPeriodontal therapy

Identifiers

PMID41985395
PMCPMC13094486

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.