Evidence map›Paper›PMID 41986358›Full record

ArticleNature communications2026

POMC neuron METTL14/m

Yuan Li, Min-Hyun Kim, Decheng Ren, Liangyou Rui

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuan LiDepartment of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0001-9845-215X
Min-Hyun KimDepartment of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0001-5108-9816
Decheng RenDepartment of Medicine, University of Chicago, Chicago, IL, USA.
Liangyou RuiDepartment of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, USA. ruily@umich.edu.ORCID http://orcid.org/0000-0001-8433-8137

Funding

The Role of Hypothalamic Slug in the Regulation of Leptin Sensitivity, Energy Balance, and Body WeightR01DK114220 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RUI, LIANGYOU · 2017 to 2024
$4.2M
Role of adipose mRNA modifications in metabolic diseaseR01DK130111 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIANGYOU RUI · 2022 to 2026
$2.4M
Role of hypothalamic SH2B1 neurocircuits and SH2B1 signal transduction pathways in obesity and metabolic diseaseR01DK141559 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIANGYOU RUI · 2025 to 2026
$1.4M
American Heart Association (American Heart Association, Inc.) 20POST35210557NIDDK NIH HHS R01 DK114220NIDDK NIH HHS R01 DK130111NIDDK NIH HHS R01 DK141559
6 · The paper itself

Abstract

METTL14 mediates N6-methyladenosine (m

Indexed as

Body WeightEnergy MetabolismMethyltransferasesNerve Tissue ProteinsNeuronsPro-OpiomelanocortinRNA-Binding ProteinsAdenosineAnimalsEpitranscriptomeFatty LiverFemaleGlucose IntoleranceHyperphagiaInsulin ResistanceMaleAdenosineMethyltransferasesMettl14 protein, mouseNerve Tissue ProteinsN-methyladenosinePro-OpiomelanocortinRNA-Binding ProteinsRNA Splicing FactorsYTHDC1 protein, mouseYTHDF2 protein, mouse

Identifiers

PMID41986358
PMCPMC13260910

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.