ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026
Lymphedema and self-reported swelling among Danish survivors of prostate cancer - prevalence, clinical associations and functional implications.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
purposeTo study lymphedema prevalence, risk factors, and the effect on physical and emotional functioning among survivors of prostate cancer.
methodsUsing the Danish SEQUEL cohort, we identified 44,101 survivors diagnosed with prostate cancer (2010-2021). Lymphedema was assessed using hospital-based treatment records of lymphedema from the National Patient Registry and for a sub-cohort of 9619 men as self-reported swelling in the leg(s) and other areas using EORTC items. Physical and emotional functioning were assessed using the EORTC QLQ-C30. Cox models and logistic regression analyses examined the associations between clinical, lifestyle factors and lymphedema treatment/swelling, and the relationship between swelling and physical/emotional functioning.
resultsAmong survivors, 2% received lymphedema treatment and 8% reported swelling. The risk of receiving lymphedema treatment was higher for survivors with metastatic vs. low-risk disease (hazard ratio (HR) 5.38, 95% confidence interval (CI) 4.50-6.44), radical prostatectomy vs. active surveillance (HR 4.80, 95% CI 3.37-6.82), and radiation or endocrine therapy vs. watchful waiting (HR 3.44, 95% CI 1.92-6.15; HR 9.01, 95% CI 5.43-14.96, respectively). Survivors with obesity vs. healthy weight had a higher risk of self-reported swelling (odds ratio (OR) 3.52, 95% CI 2.87-4.34). Swelling was associated with impaired physical (OR 3.75, 95% CI 3.20-4.41) and emotional function (OR 4.41, 95% CI 3.44-5.62).
conclusionRadical prostatectomy, radiation, endocrine therapy, metastatic disease, and obesity increase the risk of lymphedema treatment. Self-reported swelling was associated with impaired physical and emotional functioning, underscoring the need for targeted monitoring and lifestyle interventions.
Indexed as
Identifiers
41986761What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.