Evidence map›Paper›PMID 41986966›Full record

Trial reportDiabetic medicine : a journal of the British Diabetic Association2026

Safety and efficacy of intermittent fasting with or without exercise in people living with overweight or obesity and type 2 diabetes-The INTERFAST-3 study design.

Caren Sourij, Alexander Müller, Abdullah Al-Baghdadi, Faisal Aziz, Norbert J Tripolt, Peter N Pferschy, Eva Andritz, Harald Kojzar, Vanessa Stadlbauer, Sabrina Leal Garcia and 1 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Diabetic medicine : a journal of the British Diabetic Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Caren SourijDivision of Cardiology, Medical University of Graz, Graz, Austria.
Alexander MüllerCardiometabolic Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.
Abdullah Al-BaghdadiCardiometabolic Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.
Faisal AzizCardiometabolic Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.
Norbert J TripoltCardiometabolic Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.ORCID https://orcid.org/0000-0002-7566-2047
Peter N PferschyCardiometabolic Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.
Eva AndritzCardiometabolic Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.
Harald KojzarCardiometabolic Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.
Vanessa StadlbauerDivision of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria.
Sabrina Leal GarciaDepartment for Medical Psychology, Psychosomatic and Psychotherapy, Medical University of Graz, Graz, Austria.
Harald SourijCardiometabolic Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.

Funding

Austrian Science Fund
6 · The paper itself

Abstract

aimsLifestyle modification, including caloric restriction and exercise, is fundamental in the treatment of people living with overweight and type 2 diabetes mellitus (T2D). The overall aim of lifestyle intervention schemes is to reduce body weight and improve glycaemic control to reduce the future risk of diabetes-associated complications. The aim of this study is to determine whether intermittent energy restriction, exercise or their combination is best suited for reaching these targets in individuals with T2D not treated with insulin.

methodsThis randomized, controlled, monocentric parallel-group trial is designed to investigate participants living with T2D, body mass index >27 kg/m

trial registrationThe study was registered at DRKS (Deutsches Register Klinischer Studien-German Clinical Trial Register DRKS-ID: DRKS00032036)-Date of registration: 11.10.2023.

Indexed as

Caloric RestrictionDiabetes Mellitus, Type 2Exercise TherapyIntermittent FastingObesityOverweightAdultBlood GlucoseBody Mass IndexCombined Modality TherapyExerciseFemaleGlycated HemoglobinGlycemic ControlHumansMaleBlood GlucoseGlycated HemoglobinCGM (continuous glucose monitoring)exerciseintermittent energy restrictionintermittent fastinglifestyleobesitytype 2 diabetes mellitus

Identifiers

PMID41986966
PMCPMC13257894

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.