ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
ANXA2-mediated Phagocytosis Generates AR
Yong Luo, Tianlong Luo, Lingfeng Li, Qi Sun, Dongquan Li, Shanhe Huang, Zonglin Li, Weilong Lin, Yuan Ou, Tao Du and 4 more
Abstract read
In one paragraphArticle in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Tianlong LuoDepartment of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Lingfeng LiBeijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Qi SunDepartment of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Dongquan LiDepartment of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Shanhe HuangDepartment of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Zonglin LiDepartment of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Yuan OuDepartment of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Tao DuDepartment of Obstetrics and Gynecology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Funding
Beijing Bethune Charitable Foundation mnzl202001Beijing Xisike Clinical Oncology Research Foundation Y-MSDZD2022-0760,Y-tongshu2021/ms-0162China Postdoctoral Science Foundation 2025M782052Guangdong Provincial Clinical Research Center for Urological Diseases 2020B1111170006Guangdong Provincial Science and Technology Program 2023B1111030006Guangdong Provincial Science and Technology Program 2023B1212060013Guangzhou Science and Technology Key R&D Project 202206010117International Science and technology cooperation project plan of Guangdong Province 2021A0505030085Joint funds for the innovation of science and technology, Fujian province 2023Y9228National key R&D plan of China 2022YFC3602904National Natural Science Foundation of China 82173036National Natural Science Foundation of China 82403975National Natural Science Foundation of China 82472902National Natural Science Foundation of China 82503289Open research funds from the Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People' s HospitalPresident Foundation of Nanfang Hospital, Southern Medical University 2024A028Sun Yat-Sen University Clinical Research 5010 Program 2019005
6 · The paper itselfAbstract
Resistance to second-generation antiandrogens like enzalutamide (ENZ) in castration-resistant prostate cancer (CRPC) is a major clinical challenge, yet the role in the tumor microenvironment remains poorly understood. This study identifies a unique AR-positive tumor-associated macrophages (AR
Indexed as
BenzamidesDrug Resistance, NeoplasmMacrophagesNitrilesPhagocytosisPhenylthiohydantoinProstatic Neoplasms, Castration-ResistantReceptors, AndrogenTumor-Associated MacrophagesAnimalsCell Line, TumorHumansInterleukin-6MaleMiceSignal TransductionBenzamidesenzalutamideInterleukin-6NitrilesPhenylthiohydantoinReceptors, AndrogenAR+ TAMsCRPCenzalutamide resistanceIL‐6 signalingphagocytosis
Identifiers
PMID41990247
PMCPMC13335082
What Socratic holds
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