Evidence map›Paper›PMID 41990265›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue-Resident Memory T Cells via Altering Skin Microbiota.

Chun-Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S Bromberg and 1 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chun-Ling LiangSection of Immunology, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, Guangdong, China.
Yuchao ChenSection of Immunology, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, Guangdong, China.
Chuanjian LuSection of Immunology, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, Guangdong, China.
Huazhen LiuSection of Immunology, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, Guangdong, China.
Fenglian QinSection of Immunology, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, Guangdong, China.
Sisi DaiSection of Immunology, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, Guangdong, China.
Feifei QiuSection of Immunology, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, Guangdong, China.
Haiming ChenSection of Immunology, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, Guangdong, China.
Weihui LuSection of Immunology, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, Guangdong, China.
Jonathan S BrombergDepartment of Microbiology and Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Zhenhua DaiSection of Immunology, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, Guangdong, China.

Funding

Basic and Applied Basic Research Foundation of Guangdong Province 2022A1515011704Basic and Applied Basic Research Foundation of Guangdong Province 2025A1515010295Basic and Applied Basic Research Foundation of Guangdong Province 2025A1515010807Basic and Applied Basic Research Foundation of Guangdong Province 2026A1515012112National Natural Science Foundation of China 82004377National Natural Science Foundation of China 82104867Science and Technology Planning Project of Guangzhou 2023B1212060063Science and Technology Planning Project of Guangzhou 2025A03J1082
6 · The paper itself

Abstract

Psoriasis recurrence remains a common and difficult medical problem, while environmental humidity appears to have an impact on psoriasis morbidity. However, it remains unknown whether and how high humidity impacts psoriasis relapse. Using unique mouse models of psoriasis relapse, we found that high humidity exposure exacerbated psoriasis recurrence by increasing skin-resident memory CD8

Indexed as

HumidityMemory T CellsPsoriasisSkinAnimalsCD8-Positive T-LymphocytesDisease Models, AnimalHumansKeratinocytesMiceRecurrenceSkin Microbiomehumiditykeratinocytepsoriasisskin microbiometissue‐resident memory T cell (TRM)

Identifiers

PMID41990265
PMCPMC13335552

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.