ArticleJournal of global health2026
Impact of seasonal temperature variations on adverse outcomes in atrial fibrillation: comparative insights from Vigo and Murcia cohorts.
Article in Journal of global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Ambient temperature is a key environmental factor influencing cardiovascular health. In patients with atrial fibrillation (AF), seasonal variations may affect the risk of clinical events and mortality. We aimed to assess the impact of summer heat on adverse cardiovascular events in anticoagulated AF patients. Methods: In this prospective study, we included anticoagulated AF patients from two Spanish cohorts located in cities with differing climates: Murcia and Vigo. We followed patients for two years, recording ischaemic stroke/transient ischaemic attack (TIA), major bleeding, major adverse cardiovascular events (MACE), cardiovascular death, and all-cause death. Results: We included 13 629 AF patients, with a median age of 78 years (interquartile range = 71-83), of which 53.4% were female. In both cities, summer was associated with significantly lower incidence rate ratios for MACE, cardiovascular death, and all-cause death compared with other seasons (all P < 0.05). In Murcia, summer was linked to a lower risk of ischaemic stroke/TIA (adjusted hazard ratio (aHR) = 0.58; 95% confidence interval (CI) = 0.35-0.96), MACE (aHR = 0.63; 95% CI = 0.45-0.89), cardiovascular death (aHR = 0.32; 95% CI = 0.19-0.56), and all-cause death (aHR = 0.41; 95% CI = 0.30-0.56) compared with winter. In Vigo, summer was associated only with a reduced risk of all-cause death (aHR = 0.65; 95% CI = 0.56-0.76) compared to winter. When comparing summers, Murcia showed an increased risk of ischaemic stroke/TIA (aHR = 3.58; 95% CI = 1.98-6.45) and MACE (aHR = 1.86; 95% CI = 1.33-2.61) compared with Vigo. Conclusions: Summer was associated with a lower risk of adverse cardiovascular events compared with winter in patients with AF living in heat-adapted cities. However, extreme heat was associated with a significantly increased cardiovascular risk.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.