Evidence map›Paper›PMID 41991800›Full record

ArticleAesthetic plastic surgery2026

Outcomes of Body Contouring Surgery After Bariatric Surgery vs. GLP-1 Receptor Agonist-Induced Weight Loss: A Propensity Score Matched Analysis.

Jade E Smith, Noelle C Garbaccio, Morvarid Mehdizadeh, Dorien I Schonebaum, Lacey Foster, Justin J Cordero, Samuel J Lin

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jade E SmithDepartment of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 110 Francis St, Boston, MA, 02215, USA.
Noelle C GarbaccioDepartment of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 110 Francis St, Boston, MA, 02215, USA.
Morvarid MehdizadehDepartment of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 110 Francis St, Boston, MA, 02215, USA.
Dorien I SchonebaumDepartment of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 110 Francis St, Boston, MA, 02215, USA.
Lacey FosterDepartment of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 110 Francis St, Boston, MA, 02215, USA.
Justin J CorderoDepartment of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 110 Francis St, Boston, MA, 02215, USA.
Samuel J LinDepartment of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 110 Francis St, Boston, MA, 02215, USA. sjlin@bidmc.harvard.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBody contouring surgery (BCS) addresses excess skin following significant weight loss. While bariatric surgery has been the primary intervention for massive weight loss, the rise of GLP-1 receptor agonists (GLP-1 RAs) introduces a new patient population seeking BCS. Limited data exists on how GLP-1 RA-associated weight loss impacts BCS timing, procedure preferences, and complication rates.

methodsThis retrospective study used the TriNetX database to identify adults who underwent BCS following bariatric surgery or long-term GLP-1 RA therapy (≥6 prescriptions). Propensity score matching adjusted for differences in sex, age, comorbidities, and nutritional markers. Kaplan-Meier analysis evaluated the timing of BCS. Additional outcomes included differences in BCS location and complication rates between weight loss methods.

resultsAmong those undergoing BCS, GLP-1 RA users more commonly underwent breast-focused procedures than post-bariatric patients (56.9% vs. 21.7%, OR 4.772, p<0.001), while post-bariatric patients more often received abdominal procedures (84.8% vs. 42.1%, OR 0.131, p<0.001). GLP-1 RA users had more variable BCS timing, with a greater proportion undergoing surgery within the first year of weight-loss therapy. Post-bariatric patients delayed BCS with a notable increase around 500 days post-surgery. GLP-1 RA users had lower intraoperative hemorrhage rates (0.07% vs. 0.74%, OR 0.09, p=0.021). Postoperative infection, wound dehiscence, and thromboembolic events were similar between cohorts.

conclusionsReduced intraoperative bleeding during BCS suggests potential benefits from anti-inflammatory properties of GLP-1 RAs compared to bariatric surgery weight loss. Variability in BCS timing highlights the need for standardized guidelines to optimize patient outcomes as GLP-1 RA use continues to expand. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Bariatric SurgeryBody ContouringGlucagon-Like Peptide-1 Receptor AgonistsObesity, MorbidWeight LossAdultCohort StudiesDatabases, FactualFemaleHumansMaleMiddle AgedPostoperative ComplicationsPropensity ScoreRetrospective StudiesRisk AssessmentGlucagon-Like Peptide-1 Receptor AgonistsBariatric surgeryBody contouring surgeryGLP-1 receptor agonistOzempicSemaglutideWeight loss timing

Identifiers

PMID41991800

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.