Evidence map›Paper›PMID 41991819›Full record

ArticleHuman cell2026

Human peritoneal CCR2

Naofumi Takahashi, Sara A Habash, Yoshihiro Komohara, Shingo Usuki, Kei-Ichiro Yasunaga, Shinjiro Hino, Randa A Abdelnaser, Thorbjorg Einarsdottir, Takushi Nomura, Atsuko Yonemura and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Human cell, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Naofumi TakahashiDivision of Infection and Hematopoiesis, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Honjo 2-2-1, Kumamoto, 860-0811, Japan.
Sara A HabashDivision of Infection and Hematopoiesis, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Honjo 2-2-1, Kumamoto, 860-0811, Japan.
Yoshihiro KomoharaDepartment of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Shingo UsukiLiaison Laboratory Research Promotion Center, Kumamoto University, Kumamoto, Japan.
Kei-Ichiro YasunagaLiaison Laboratory Research Promotion Center, Kumamoto University, Kumamoto, Japan.
Shinjiro HinoDepartment of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto, Japan.
Randa A AbdelnaserDivision of Infection and Hematopoiesis, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Honjo 2-2-1, Kumamoto, 860-0811, Japan.
Thorbjorg EinarsdottirDivision of Virology and Pathology, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, Japan.
Takushi NomuraDivision of Virology and Pathology, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, Japan.
Atsuko YonemuraDivision of Carcinogenesis, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.
Takatsugu IshimotoDivision of Carcinogenesis, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.
Shinya SuzuDivision of Infection and Hematopoiesis, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Honjo 2-2-1, Kumamoto, 860-0811, Japan. ssuzu06@kumamoto-u.ac.jp.ORCID http://orcid.org/0000-0003-2531-4770

Funding

Japanese Society of Hematology 2024Japan Society for the Promotion of Science 20H03725Japan Society for the Promotion of Science 22K08456
6 · The paper itself

Abstract

Recent studies in mouse models have demonstrated that macrophages in adult tissues are maintained not only by the differentiation of bone marrow-derived monocytes but also by the proliferation of macrophages originating from the yolk sac or fetal liver. However, the extent to which this paradigm shift occurs in human tissues is not fully understood. In this study, we detected a human peritoneal macrophage subset that exhibited embryonic origin-like phenotypes. Macrophages in the ascites of patients with gastric cancer were divided into CCR2

Indexed as

MacrophagesMacrophages, PeritonealReceptors, CCR2AnimalsAscitesBiomarkersCell DifferentiationCell ProliferationGene ExpressionHumansKi-67 AntigenPhenotypeBiomarkersCCR2 protein, humanKi-67 AntigenReceptors, CCR2Ascitic fluidBone marrow-derivedCCR2Embryo-derivedMacrophages

Identifiers

PMID41991819

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.