Evidence map›Paper›PMID 41991933›Full record

ArticleNature communications2026

PcabHLH58/PcabHLH151 regulates adventitious root development and nitrogen uptake in poplar.

Hantian Wei, Xinglu Zhou, Xiaodong Xiang, Jiujun Du, Yongxia Bai, Min Zhang, Xueqin Song, Guanzheng Qu, Lei Zhang, Jianjun Hu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hantian Wei *State Key Laboratory of Tree Genetics and Breeding, Research Institute of Forestry, Chinese Academy of Forestry, Northeast Forestry University, Beijing, China.
Xinglu Zhou *State Key Laboratory of Tree Genetics and Breeding, Research Institute of Forestry, Chinese Academy of Forestry, Northeast Forestry University, Beijing, China.ORCID http://orcid.org/0000-0003-4326-2441
Xiaodong XiangState Key Laboratory of Tree Genetics and Breeding, Research Institute of Forestry, Chinese Academy of Forestry, Northeast Forestry University, Beijing, China.
Jiujun DuState Key Laboratory of Tree Genetics and Breeding, Research Institute of Forestry, Chinese Academy of Forestry, Northeast Forestry University, Beijing, China.ORCID http://orcid.org/0000-0003-0359-6666
Yongxia BaiState Key Laboratory of Tree Genetics and Breeding, Research Institute of Forestry, Chinese Academy of Forestry, Northeast Forestry University, Beijing, China.
Min ZhangState Key Laboratory of Tree Genetics and Breeding, Research Institute of Forestry, Chinese Academy of Forestry, Northeast Forestry University, Beijing, China.
Xueqin SongState Key Laboratory of Tree Genetics and Breeding, Research Institute of Forestry, Chinese Academy of Forestry, Northeast Forestry University, Beijing, China.
Guanzheng QuState Key Laboratory of Tree Genetics and Breeding, Research Institute of Forestry, Chinese Academy of Forestry, Northeast Forestry University, Beijing, China.
Lei ZhangState Key Laboratory of Tree Genetics and Breeding, Research Institute of Forestry, Chinese Academy of Forestry, Northeast Forestry University, Beijing, China. leizhang1142@caf.ac.cn.
Jianjun HuState Key Laboratory of Tree Genetics and Breeding, Research Institute of Forestry, Chinese Academy of Forestry, Northeast Forestry University, Beijing, China. hujj@caf.ac.cn.ORCID http://orcid.org/0000-0002-5177-399X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a crucial ecological shelterbelt and timber species in China, Populus relies on adventitious root (AR) formation and root architecture for its ecological adaptability and clonal propagation efficiency. Two key root trait-related genes, PcabHLH58 and PcabHLH151, were identified through genome-wide association studies (GWAS) in Populus cathayana. Single or double mutations of PcabHLH58 and PcabHLH151 significantly inhibited AR development and nitrogen uptake in poplar. Furthermore, both genes can form homodimers or heterodimers to modulate the expression of PcaSCL33 and PcaPLT1 during AR development. The higher expression level and stronger regulatory capacity of PcabHLH58 imply its more critical role in the AR development. Additionally, PcaWOX5 was found to be modulated through both the PcabHLH58/PcabHLH151-PcaSCL33/PcaSHR and PcabHLH58/PcabHLH151-PcaPLT1 pathway. PcaPAR1 was identified as a feedback regulatory node in modulating the regulatory activities of both PcabHLH58 and PcabHLH151. Collectively, this study elucidates a novel regulatory network involving root development in poplar and provides foundational insights for future genetic breeding efforts.

Indexed as

NitrogenPlant ProteinsPlant RootsPopulusGene Expression Regulation, PlantGenes, PlantGenome-Wide Association StudyMutationPlants, Genetically ModifiedNitrogenPlant Proteins

Identifiers

PMID41991933
PMCPMC13287712

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.