ArticleJournal of nanobiotechnology2026
Multi-enzymatic catalysis copper ceria-polyphenol nanozyme for balancing peroxidase catalysis and reactive oxygen scavenging: a synergistic strategy for enhancing drug-resistant bacteria eradication.
Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Strong catalysis and novel copper-induced cell death enable copper-based nanozymes to present good bactericidal capacity against antibiotic-resistant pathogens, but their aspect of the balance between low ROS and low-dose antibacterial performance remains a significant challenge. Herein, an innovative copper/cerium (Cu/Ce)-doped metal-polyphenol network nanozyme (CCP) was synthesized for synergistically modulating the multi-enzymatic activities and enhancing methicillin-resistant Staphylococcus aureus (MRSA) eradication, where Cu and Ce individually decorated on carbon nanosheet skeleton. Benefited from the Cu/Ce dual-site structure, CCP exhibited remarkable multi-enzymatic (superoxide dismutase-, peroxidase-, glutathione peroxidase-, and nicotinamide adenine dinucleotide peroxidase-like) and
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