ArticlebioRxiv : the preprint server for biology2026
RUNX1-deficiency drives immune-active ER
Sen Han, Dongxi Xiang, Xueqing Chen, Dongyi Zhao, Guyu Qin, Roderick T Bronson, Zhe Li
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Sen HanDivision of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Dongxi XiangDivision of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Xueqing ChenDivision of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Dongyi ZhaoDivision of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Guyu QinDivision of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Roderick T BronsonRodent Histopathology, Harvard Medical School, Boston, Massachusetts 02115, USA.
Zhe LiDivision of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.ORCID 0000-0002-3434-0885 Funding
Interplay of mammary luminal cells and environmental factors in establishing p53-deficient premalignant fieldR01CA222560 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI LI, ZHE · 2018 to 2022
$1.9MDNA damage-related stemness program during BRCA1 breast cancer initiationR01CA295752 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI Zhe Li · 2025 to 2026
$1.1MDevelopment of a clinically relevant mouse model of ER+ breast cancerR21CA256468 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI LI, ZHE · 2021 to 2022
$414kNCI NIH HHS R01 CA222560NCI NIH HHS R01 CA295752NCI NIH HHS R21 CA256468
6 · The paper itselfAbstract
Indexed as
ER+ breast cancerestrogen receptorinterferon signalingluminal mammary epithelial cellsmacrophagesp53RB1RUNX1STAT1T cells
Identifiers
PMID41993340
PMCPMC13081936
What Socratic holds
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