Evidence map›Paper›PMID 41993501›Full record

ArticlebioRxiv : the preprint server for biology2026

The chitin receptor-interacting protein LIK1 regulates extracellular ATP signaling via interaction with P2K1 in

Jinrong Wan, Mengran Yang, Jae Song, Chunhui Xu, Sung-Hwan Cho, Mowei Zhou, Ljiljana Pasa-Tolic, Bing Yang, Dong Xu, Gary Stacey

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jinrong WanDivision of Plant Sciences and Technology, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA.
Mengran YangDivision of Plant Sciences and Technology, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA.
Jae SongDivision of Plant Sciences and Technology, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA.ORCID 0000-0003-4324-9335
Chunhui XuDepartment of Electrical Engineering and Computer Science, C.S. Bond Life Sciences Center, Institute for Data Science and Informatics, University of Missouri, Columbia, Missouri, USA.
Sung-Hwan ChoDivision of Plant Sciences and Technology, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA.
Mowei ZhouEnvironmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington, USA.
Ljiljana Pasa-TolicEnvironmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington, USA.
Bing YangDivision of Plant Sciences and Technology, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA.
Dong XuDepartment of Electrical Engineering and Computer Science, C.S. Bond Life Sciences Center, Institute for Data Science and Informatics, University of Missouri, Columbia, Missouri, USA.
Gary StaceyDivision of Plant Sciences and Technology, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA.

Funding

DORN1 defines a new family of receptor kinase purinoreceptors (P2K)R01GM121445 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI STACEY, GARY · 2017 to 2024
$2.5M
NIGMS NIH HHS R01 GM121445
6 · The paper itself

Abstract

Previously, the chitin receptor-interacting protein kinase LIK1 (LysM receptor kinase 1/CERK1-interacting kinase) was shown to play an important role in regulating chitin signaling and plant defense. A limited proteolysis proteomics study revealed several LIK1-derived peptides that showed differential abundance between ATP-treated and mock-treated Arabidopsis samples, suggesting a possible involvement of LIK1 in extracellular ATP (eATP) signaling. To explore this possibility,

Indexed as

extracellular ATPjasmonic acidLIKP2K1signal transduction

Identifiers

PMID41993501
PMCPMC13082086

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.