Evidence map›Paper›PMID 41993541›Full record

ArticlebioRxiv : the preprint server for biology2026

A transcriptomic axis aligns with in vivo functional dynamics in hippocampal inhibitory circuits.

Hyun Choong Yong, Stephanie A Herrlinger, Margaret E Conde Paredes, Cliodhna K O'Toole, Juyoun Yoo, Bovey Y Rao, Tiberiu S Mihaila, Jingcheng Shi, Subhrajit Dey, Erdem Varol and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hyun Choong YongMortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University; New York, NY, USA.ORCID 0000-0002-1841-6317
Stephanie A HerrlingerMortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University; New York, NY, USA.
Margaret E Conde ParedesMortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University; New York, NY, USA.
Cliodhna K O'TooleMortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University; New York, NY, USA.
Juyoun YooMortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University; New York, NY, USA.
Bovey Y RaoMortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University; New York, NY, USA.
Tiberiu S MihailaMortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University; New York, NY, USA.
Jingcheng ShiMortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University; New York, NY, USA.
Subhrajit DeyTandon School of Engineering, New York University; New York, NY, USA.
Erdem VarolTandon School of Engineering, New York University; New York, NY, USA.
Attila LosonczyMortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University; New York, NY, USA.

Funding

Optimization, application and dissemination of high-speed hybrid multiphoton volumetric imaging technologiesU01NS115530 · NINDS · ROCKEFELLER UNIVERSITY · PI LOSONCZY, ATTILA, VAZIRI, ALIPASHA · 2020 to 2023
$4.7M
Microcircuit, cellular and molecular dissection of impaired hippocampal function in a mouse model of the 22q11.2 deletionR01MH124047 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GOGOS, JOSEPH A, LOSONCZY, ATTILA · 2020 to 2024
$3.8M
Experimental and modeling investigations into microcircuit, cellular and subcellular determinants of hippocampal ensemble recruitment to contextual representationsR01MH124867 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LOSONCZY, ATTILA, POIRAZI, PANAYIOTA · 2021 to 2025
$3.4M
Control of Axon Initial Segment in EpilepsyR01NS121106 · NINDS · STANFORD UNIVERSITY · PI LOSONCZY, ATTILA, SOLTESZ, IVAN · 2021 to 2025
$3.4M
Dissecting the role of the dentate gyrus microcircuit to improve cognitive discrimination in aging and Alzheimer's DiseaseRF1AG080818 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FUSI, STEFANO, HEN, RENE · 2023 to 2023
$2.5M
Activity-dependent endocannabinoid control in epilepsyR01NS131728 · NINDS · STANFORD UNIVERSITY · PI Attila Losonczy, IVAN SOLTESZ · 2023 to 2026
$2.3M
Local Circuit Control of Rapid Plasticity and Tunable Ensemble Formation in the HippocampusR01NS133381 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI Attila Losonczy, IVAN SOLTESZ · 2026 to 2026
$752k
Transcriptional basis of stereotyped neural architecturesR00MH128772 · NIMH · NEW YORK UNIVERSITY · PI Erdem Varol · 2024 to 2026
$734k
NIA NIH HHS RF1 AG080818NIMH NIH HHS R00 MH128772NIMH NIH HHS R01 MH124047NIMH NIH HHS R01 MH124867NINDS NIH HHS R01 NS121106NINDS NIH HHS R01 NS131728NINDS NIH HHS R01 NS133381NINDS NIH HHS U01 NS115530
6 · The paper itself

Abstract

Linking molecular identity to function

Identifiers

PMID41993541
PMCPMC13081834

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.