ArticleFrontiers in cardiovascular medicine2026
The role and mechanisms of gut microbiota in blood pressure regulation and cardiovascular health in hypertensive patients: an intervention study based on probiotics and high-fiber diets.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: This study aimed to investigate the effects and mechanisms of probiotics combined with a high-fiber diet (PHFD) on blood pressure regulation and cardiovascular health in hypertensive patients. Methods: A retrospective cohort study was conducted involving 322 hypertensive patients admitted between January 2020 and June 2023. Patients were defined into two groups: conventional treatment ( Results: After the intervention, the PHFD group showed significantly lower systolic BP ( Conclusion: Probiotics and high-fiber diet interventions effectively modulate gut microbiota and SCFAs, resulting in significant improvements in blood pressure and cardiovascular health among hypertensive patients. These findings highlight the potential of integrated gut microbiota-targeted therapies as novel strategies for hypertension management.
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