Evidence map›Paper›PMID 41993970›Full record

ReviewBiomedical reports2026

Syntaxin1A in synaptopathies: From molecular mechanisms to therapeutic implications in neurological disorders (Review).

Yating Huang, Jun Xi, Baoling Su, Peipei Wang, Cuimei Xie, Yifan Yuan, Xiaoping Yin, Bing Bao

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biomedical reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yating HuangDepartment of Neurology, College of First Clinical Medical Science, Gannan Medical University, Ganzhou, Jiangxi 341000, P.R. China.
Jun XiDepartment of Neurology, College of Clinical Medical Science, Jiujiang University, Jiujiang, Jiangxi 332000, P.R. China.
Baoling SuDepartment of Neurology, University of Shanghai for Science and Technology, Shanghai 200000, P.R. China.
Peipei WangDepartment of Neurology, College of Clinical Medical Science, Jiujiang University, Jiujiang, Jiangxi 332000, P.R. China.
Cuimei XieDepartment of Neurology, College of Clinical Medical Science, Jiujiang University, Jiujiang, Jiangxi 332000, P.R. China.
Yifan YuanDepartment of Neurology, Affiliated Hospital of Jiujiang University, Jiujiang, Jiangxi 332000, P.R. China.
Xiaoping YinDepartment of Neurology, College of Clinical Medical Science, Jiujiang University, Jiujiang, Jiangxi 332000, P.R. China.
Bing BaoDepartment of Neurology, College of First Clinical Medical Science, Gannan Medical University, Ganzhou, Jiangxi 341000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Syntaxin1A (STX1A) is a presynaptic membrane protein that is abundantly expressed in the central nervous system. It is a key member of the soluble N-ethylmaleimide sensitive factor attachment protein receptor protein family. Notably, STX1A acts as a 'molecular hub' in neural networks by regulating presynaptic membrane fusion with synaptic vesicles and the subsequent release of neurotransmitters. In addition to this function, STX1A is crucial for neuronal development, synaptic plasticity, and ion channel regulation. The deficiency or variation of

Indexed as

ADADHDASDepilepsyISmigraineneurological disordersPDSTX1A

Identifiers

PMID41993970
PMCPMC13082830

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.