ArticleJournal of dentistry (Shiraz, Iran)2026
Association of Vitamin D Receptor Gene Polymorphisms with Periodontitis.
Article in Journal of dentistry (Shiraz, Iran), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
Background: Considering the role of vitamin D in regulation of the bone metabolism and the immune system, some have suggested the effect of vitamin D receptor gene polymorphism in susceptibility to periodontitis. Purpose: We aimed to determine the association between vitamin D receptor (VDR) gene polymorphisms Materials and Method: In this case-control study, 51 patients with stage Ⅲ periodontitis (case group) and 51 without (control group) were enrolled. Blood samples were taken to analyze the single nucleotide polymorphism (SNP) using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) after DNA extraction. Finally, the data were analyzed using SPSS software version 17, SNPStats, using Chi-square and t-test. Results: The allelic frequencies of SNP1 ( Conclusion: No significant association was found between VDR gene polymorphisms and periodontitis.
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