ArticleResearch square2026
Design and Synthesis of Odorranalectin-Derived Peptides for RNA Binding.
Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
Small interfering RNA (siRNA) holds significant therapeutic potential for a broad range of diseases, including diseases of the central nervous system, yet its clinical translation remains limited by the lack of efficient and targeted delivery strategies, largely due to poor membrane permeability. To address this challenge, we developed a multifunctional RNA delivery platform by integrating positively charged cell-penetrating peptide sequences into the lectin-mimicking cyclic peptide odorranalectin (OL), which has demonstrated nose-to-brain transport capability. Placement of the cationic sequence at the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.