Evidence map›Paper›PMID 41994129›Full record

ArticleResearch square2026

miR-34 regulates stress-induced depression-like state through the

Shreyasi Mitra, Amit Kumar, Aman Gill, Majid Ali, Aman Bashar, Puli Chandramouli Reddy, Geetanjali Chawla

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shreyasi MitraRNA Biology Laboratory, Department of Life Sciences, School of Natural Sciences, Shiv Nadar Institution of Eminence, Uttar Pradesh-201314, India.
Amit KumarRNA Biology Laboratory, Department of Life Sciences, School of Natural Sciences, Shiv Nadar Institution of Eminence, Uttar Pradesh-201314, India.
Aman GillRNA Biology Laboratory, Department of Life Sciences, School of Natural Sciences, Shiv Nadar Institution of Eminence, Uttar Pradesh-201314, India.
Majid AliRNA Biology Laboratory, Department of Life Sciences, School of Natural Sciences, Shiv Nadar Institution of Eminence, Uttar Pradesh-201314, India.
Aman BasharCSIR-Institute of Genomics and Integrative Biology, Council of Scientific and Industrial Research (CSIR), Delhi-110025, India.
Puli Chandramouli ReddyCenter of Excellence in Epigenetics, Department of Life Sciences, School of Natural Sciences, Shiv Nadar Institution of Eminence, Uttar Pradesh-201314, India.
Geetanjali ChawlaRNA Biology Laboratory, Department of Life Sciences, School of Natural Sciences, Shiv Nadar Institution of Eminence, Uttar Pradesh-201314, India.ORCID 0000-0003-0354-3716

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Major depressive disorder (MDD) is a complex and recurrent neuropsychiatric disorder with poorly understood molecular underpinnings. Psychosocial stress is a major environmental risk factor, yet the mechanisms linking stress exposure to behavioral outcomes remain unclear. MicroRNAs (miRNAs) have emerged as key regulators linking environmental stress to changes in gene expression in mood disorders. Here, using stress-induced rodent and

Indexed as

behaviourdepressionMicroRNAsmiR-34stress

Identifiers

PMID41994129
PMCPMC13082156

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.