Evidence map›Paper›PMID 41994620›Full record

ArticleBrain communications2026

The heartbeat evoked potential and the prediction of functional seizure semiology.

Rohan Kandasamy, Samia Elkommos, Ineke A van Rossum, David Martin-Lopez, Akihiro Koreki, Fiona Farrell, Suzanne O'Sullivan, Beate Diehl, Fahmida A Chowdhury, Hugo Critchley and 3 more

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Article in Brain communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rohan KandasamyDepartment of Clinical Neurophysiology, National Hospital of Neurology and Neurosurgery, London WC1N 3BG, UK.ORCID https://orcid.org/0000-0001-8554-2658
Samia ElkommosSchool of Neuroscience, King's College, London WC2R 2LS, UK.
Ineke A van RossumLeiden University Medical Centre, Leiden 2333 ZA, The Netherlands.ORCID https://orcid.org/0000-0002-0999-7156
David Martin-LopezAtkinson Morley Regional Neurosciences Centre, St George's University Hospitals, London SW17 0QT, UK.
Akihiro KorekiUCL Queen Square Institute of Neurology, London WC1N 3BG, UK.
Fiona FarrellNational Hospital of Neurology and Neurosurgery Epilepsy Group, London WC1N 3BG, UK.
Suzanne O'SullivanDepartment of Clinical Neurophysiology, National Hospital of Neurology and Neurosurgery, London WC1N 3BG, UK.
Beate DiehlDepartment of Clinical Neurophysiology, National Hospital of Neurology and Neurosurgery, London WC1N 3BG, UK.
Fahmida A ChowdhuryDepartment of Clinical Neurophysiology, National Hospital of Neurology and Neurosurgery, London WC1N 3BG, UK.
Hugo CritchleyDepartment of Clinical Neuroscience, Brighton and Sussex Medical School, University of Sussex, Brighton BN1 9PX, UK.
Matthew C WalkerUCL Queen Square Institute of Neurology, London WC1N 3BG, UK.ORCID https://orcid.org/0000-0002-0812-0352
Sarah GarfinkelUCL Institute of Cognitive Neuroscience, London WC1N 3AR, UK.
Mahinda YogarajahUCL Queen Square Institute of Neurology, London WC1N 3BG, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional seizures (FSs) are common, but distinguishing FS from epileptic seizures (ESs) can be challenging, and the pathophysiology is not well-understood. The heartbeat evoked potential (HEP) reflects the central processing of cardiac signals and bodily attention. Our group previously demonstrated HEP differences between FS and ES. Here, we sought to replicate these HEP findings in an independent retrospective sample and observe effects of semiology. Because we lacked symptom reporting at the time of a seizure, in the second part of the study we examined whether HEP modulation was associated with real-time bodily symptom reporting in a second retrospective sample of individuals with functional or vasovagal syncope where symptom data was available. In the first part, we identified FS (

Indexed as

dissociative seizuresinteroceptionnon-epileptic attack

Identifiers

PMID41994620
PMCPMC13080701

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.