Evidence map›Paper›PMID 41995320›Full record

ArticleApplied and environmental microbiology2026

Systems metabolic engineering for hydroxytyrosol production in

Wenjing Jiang, Zhichao Chen, Wenjing Fan, Changgeng Li, Lanxiao Li, Zichen Yu, Xu Li, Qingyang Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenjing JiangCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, People's Republic of China.ORCID 0009-0003-5273-4110
Zhichao ChenCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, People's Republic of China.
Wenjing FanCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, People's Republic of China.
Changgeng LiCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, People's Republic of China.
Lanxiao LiCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, People's Republic of China.
Zichen YuCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, People's Republic of China.
Xu LiCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, People's Republic of China.
Qingyang XuCollege of Biotechnology, Tianjin University of Science & Technology, Tianjin, People's Republic of China.ORCID 0000-0003-1619-3508

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydroxytyrosol (HT), the primary functional component of olive oil, presents significant challenges for microbial biosynthesis due to its inherent chemical properties and fermentation requirements. In this study, we describe the modular engineering of HT production in

Indexed as

Escherichia coliMetabolic EngineeringPhenylethyl AlcoholAlcohol DehydrogenaseCarboxy-LyasesEscherichia coli ProteinsFermentationMixed Function OxygenasesSaccharomyces cerevisiae3,4-dihydroxyphenylethanol4-hydroxyphenylacetate 3-monooxygenaseAlcohol DehydrogenaseCarboxy-LyasesEscherichia coli ProteinsMixed Function OxygenasesPhenylethyl Alcoholphenylpyruvate decarboxylaseEscherichia colihydroxytyrosolmetabolic engineering

Identifiers

PMID41995320
PMCPMC13188884

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.