ReviewOdontology2026
Advanced biomimetic mineralization approaches for enamel and dentin regeneration: a review.
Review in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Advances in Regenerative Dentistry: From Biological Mechanisms to Clinical Translation.Life (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biomimetic mineralization represents a promising strategy to replicate the natural processes of amelogenesis and dentinogenesis through proteins, peptides, ion delivery systems, enzyme-mimicking catalysts, and nanotechnology-based materials. Restoring enamel and dentin represents a major challenge in restorative dentistry due to their complex hierarchical architecture and limited intrinsic repair capacity. Conventional restorative materials can restore function but often fail to reproduce the mechanical, aesthetic, and biological properties of natural tissues and are prone to long-term degradation and secondary caries. Recent advances, including cell-free mineralization systems, self-assembling peptides, and nanostructured scaffolds, aim to mimic the structural and chemical environment of developing dental tissues, offering potential for non-invasive, biologically integrated, and durable restorations. This review highlights current progress in elucidating mineralization mechanisms, recent innovations in biomimetic strategies, and evidence from experimental and translational studies on enamel and dentin regeneration. Particular attention is given to emerging materials such as self-assembling peptides, calcium-phosphate based systems, and natural biomolecules including keratin and polyphenols. Finally, future perspectives are outlined, emphasizing integration with tissue engineering bioactive, biomimetic and smart biomaterials to enable functional and long-lasting dental tissue regeneration.
Indexed as
Identifiers
41996017What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.