Evidence map›Paper›PMID 41998070›Full record

ArticleScientific reports2026

The role of synbiotic in controlling Salmonella infection in broilers.

Atef A Salim, Nesreen A Mohamed, Ghada A El-Gammal, Rania I El-Meslemany, Nessreen F Anwar

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Atef A SalimPoultry Diseases Unit, Kafrelsheikh Regional Laboratory, Agricultural Research Center (ARC), Animal Health Research Institute, Giza, Egypt.
Nesreen A MohamedBiochemistry, Nutritional Deficiency Diseases and Toxicology Unit, Kafrelsheikh Regional Laboratory, Agricultural Research Center (ARC), Animal Health Research Institute, Giza, Egypt.
Ghada A El-GammalBacteriology Unit, Kafrelsheikh Regional Laboratory, Agricultural Research Center (ARC), Animal Health Research Institute, Giza, Egypt. elgammalghada28@gmail.com.
Rania I El-MeslemanyBacteriology, Reference Laboratory for Veterinary Quality Control on Poultry Production Damanhour Branch, Agricultural Research Center (ARC), Animal Health Research Institute, Giza, Egypt.
Nessreen F AnwarPathology Unit, Aswan Regional Laboratory, Agricultural Research Center (ARC), Animal Health Research Institute, Giza, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salmonellosis significantly affects poultry production sector and public health, through the emergence of multi-drug resistant (MDR) strains, which require attempts to use sustainable, safe, and effective alternatives. This study was carried out over the period spanning 2024 to 2025 and involved two steps. The first step included Salmonella isolation and characterization from 25 diseased poultry farms from various regions of Northwest Delta, Egypt, focusing on some of their virulence genes and sensitivity to antibiotics. The second experimental step involved exploring the effectiveness of synbiotic compared with traditional antibiotics in reducing Salmonella colonization and their impact on poultry performance, including growth performance, immunological parameters, and pathological changes after artificial infection. The result revealed the presence of Salmonella sp. in 16% (40/250) of examined samples, including 3 serotypes, Salmonella Papuana, Salmonella Enteritidis, and Salmonella Kentucky, with different values of MAR index ranging between 0.21 and 0.43. Marked resistances were recorded against amoxicillin, lincomycin and spiramycin (100%), followed by ampicillin (75%), while the highest sensitivity was observed toward amikacin, gentamicin, cefotaxime, colistin sulfate, and streptomycin. All Salmonella strains contained the invA and enterotoxin gene (stn), whereas spvC was detected in 75% of isolates. The study declared the impact of the supplementation of synbiotic in feed in improvement of the growth performance parameters, decreased Salmonella colonization, reduced severity of clinical signs and postmortem lesions relative to the other groups (untreated group and antibiotic treated group), in addition to its considerable improvement in hematological, biochemical, and immunological parameters and less pathological alterations than other groups.

Indexed as

ChickensPoultry DiseasesSalmonellaSalmonella Infections, AnimalSynbioticsAnimalsAnti-Bacterial AgentsEgyptMicrobial Sensitivity TestsVirulenceAnti-Bacterial AgentsAntibiotic resistanceBiochemical parametersLesionsPathological changesSalmonellaSynbiotic

Identifiers

PMID41998070
PMCPMC13090347

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.