ArticleBMC chemistry2026
Eco-friendly approach for spectrofluorimetric determination of moxifloxacin in pharmaceutical formulations and biological samples using deep eutectic solvents.
Article in BMC chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
A novel green spectrofluorimetric technique was developed for the quantitative analysis of moxifloxacin (MOXI) in pure form, commercial formulations, and biological samples utilising deep eutectic solvent (DES) instead of an aqueous medium. Ethaline, a deep eutectic solvent composed of choline chloride and ethylene glycol, was utilised as the environmentally friendly solvent system. The approach exhibited enhanced analytical performance compared to water-based analysis, evidenced by a 1.2-fold increase in fluorescence intensity and a blue shift in both excitation and emission wavelengths. The calibration graph demonstrated a linear association between fluorescence intensity and moxifloxacin concentrations ranging from 0.2 to 10 µg mL
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