Evidence map›Paper›PMID 42003810›Full record

ArticleArtificial organs2026

Condensation in a Membrane Oxygenator Analyzed by Bronchoscopy and Ultrasonography.

Shin-Ichiro Nagao, Kazumasa Orihashi

Abstract read
In one paragraph

Article in Artificial organs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shin-Ichiro NagaoDivision of Clinical Engineering, Chikamori Hospital, Kochi-City, Kochi, Japan.
Kazumasa OrihashiLiaison Healthcare Engineering Section, Kochi Medical School, Nankoku-City, Kochi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo elucidate the mechanism of condensation-related oxygenator dysfunction (CROD) and explore preventive strategies, we directly visualized the interior of a membrane oxygenator using bronchoscopy and ultrasonography and evaluated the effect of external warming.

methodsThe CROD model consisted of a circuit incorporating a membrane oxygenator perfused with water at 3 L/min and supplied with gas (50% O

resultsIn the CROD model, condensation appeared at approximately 2 h, predominantly in the cooler outer zone. The droplet area increased over time and showed a strong positive association with gas-supply pressure (r = 0.9041). Gas flushing partially reduced both parameters but did not restore baseline values. Ultrasonographic findings remained similar to those of a dry oxygenator. In the heating model, the outer zone was approximately 1°C warmer than the inner zone, and no visible condensation developed over 24 h, with stable gas pressure.

conclusionsTwo-directional visualization demonstrated that outlet-surface condensation, mainly in the outer zone, was associated with elevated gas-supply pressure in this mechanistic model of CROD. Uniform external heating suppressed condensation, suggesting that temperature control and early detection may represent practical strategies to mitigate CROD.

Indexed as

BronchoscopyExtracorporeal Membrane OxygenationOxygenators, MembraneEquipment DesignHot TemperatureHumansOxygenPressureUltrasonographyOxygenbronchoscopyECMOheatingoxygenator dysfunctionultrasonography

Identifiers

PMID42003810
PMCPMC13397194

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.