Evidence map›Paper›PMID 42003848›Full record

SynthesisChemical record (New York, N.Y.)2026

Precision Design of Single-Atom Catalysts for High-Performance Biosensors.

Xianhong Wang, Xinlu Ye, Zhenhui Li, Neda Anastassova, Haiyue Yang, Dang Zhang, Viktor Korzhikov-Vlakh, Zhengxiang Zhong, Guangming Nie, Ke Zhang and 5 more

Abstract readReviewSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Chemical record (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xianhong WangState Key Laboratory of Advanced Inorganic Fibers and Composites, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China.
Xinlu YeState Key Laboratory of Advanced Inorganic Fibers and Composites, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China.
Zhenhui LiSchool of New Energy and Advanced Materials, Liaoning Petrochemical University, Fushun, China.ORCID 0000-0002-2383-2921
Neda AnastassovaInstitute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Haiyue YangState Key Laboratory of Advanced Inorganic Fibers and Composites, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China.
Dang ZhangState Key Laboratory of Advanced Inorganic Fibers and Composites, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China.
Viktor Korzhikov-VlakhInstitute of Chemistry, Saint-Petersburg State University, St. Petersburg, Russia.
Zhengxiang ZhongState Key Laboratory of Advanced Inorganic Fibers and Composites, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China.
Guangming NieState Key Laboratory of Advanced Optical Polymer and Manufacturing Technology, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, China.
Ke ZhangState Key Laboratory of Advanced Inorganic Fibers and Composites, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China.
Kwangsoo ShinDepartment of Polymer Science and Engineering and Program in Environmental and Polymer Engineering, Resource-Recycling Electronic Materials Laboratory, Inha University, Incheon, Republic of Korea.
Xingwen ZhangState Key Laboratory of Advanced Inorganic Fibers and Composites, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China.ORCID 0009-0001-0347-4557
Min YangState Key Laboratory of Advanced Inorganic Fibers and Composites, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China.ORCID 0000-0002-2319-8086
Wei GuoKey Laboratory of Photochemical Biomaterials and Energy Storage Materials, Heilongjiang Province and College of Chemistry and Chemical Engineering, Harbin Normal University, Harbin, China.ORCID 0000-0001-5445-7872
Lei WangState Key Laboratory of Advanced Inorganic Fibers and Composites, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China.ORCID 0000-0002-9522-3623

Funding

National Natural Science Foundation of China 52473109National Natural Science Foundation of China 52530002
6 · The paper itself

Abstract

Biosensors are crucial in fields like diagnostics but face challenges in sensitivity, selectivity, and stability. Single-atom catalysts (SACs), with atomically dispersed metalsites and precise active centers, provide high catalytic activity that can address these issues. However, their poor biocompatibility hinders integration. Through tailored design, SACs can achieve both high catalysis and biocompatibility. A systematic review connecting their atomic structure to biosensing performance is still needed. This review fills that gap by analyzing recent SAC-based biosensors. It explains how SAC structure governs sensing in electrochemical, colorimetric, electrochemiluminescence, and photoelectrochemical platforms, highlighting improved real-sample performance. Challenges in synthesis and application are discussed, along with future directions for advancing biosensing via single-atom catalysis.

Indexed as

Biosensing TechniquesCatalysisElectrochemical Techniquesbiosensorsdetection mechanismselectrochemiluminescencesingle‐atom catalysts

Identifiers

PMID42003848
PMCPMC13480785

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.