Evidence map›Paper›PMID 42004009›Full record

ArticleBrain communications2026

A thalamic perspective of (un)consciousness in pharmacological and pathological states in humans.

Dorottya Szocs, Dian Lyu, Andrea I Luppi, Peter Coppola, Rebecca E Woodrow, Guy B Williams, Judith Allanson, John D Pickard, Adrian M Owen, Lorina Naci and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dorottya SzocsDepartment of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0SP, UK.ORCID https://orcid.org/0009-0009-5809-3258
Dian LyuDepartments of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94304, USA.ORCID https://orcid.org/0000-0002-9363-7670
Andrea I LuppiDepartment of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0SP, UK.ORCID https://orcid.org/0000-0002-3461-6431
Peter CoppolaDepartment of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0SP, UK.
Rebecca E WoodrowDepartment of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0SP, UK.
Guy B WilliamsDepartment of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0SP, UK.
Judith AllansonDepartment of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0SP, UK.
John D PickardDepartment of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0SP, UK.ORCID https://orcid.org/0000-0002-5762-6667
Adrian M OwenThe Brain and Mind Institute, Department of Psychology, The University of Western Ontario, London, ON N6A 5B7, Canada.ORCID https://orcid.org/0000-0002-5738-3765
Lorina NaciInstitute for Neuroscience, Trinity College Dublin, Dublin D02, Ireland.ORCID https://orcid.org/0000-0001-9630-3978
David K MenonDepartment of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0SP, UK.ORCID https://orcid.org/0000-0002-3228-9692
Emmanuel A StamatakisDepartment of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0SP, UK.ORCID https://orcid.org/0000-0001-6955-9601

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, there is substantial ongoing discussion around the functional role of the thalamus in consciousness. What is missing in the literature, however, is a systematic investigation of the relevance of specific thalamic nuclei in pharmacologically and pathologically altered states of consciousness in humans. Using resting-state functional magnetic resonance imaging in both healthy anaesthetized volunteers (

Indexed as

disorders of consciousnessfMRIminimally conscious statethalamusunresponsive wakefulness syndrome

Identifiers

PMID42004009
PMCPMC13084198

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.