ArticleAlzheimer's & dementia (Amsterdam, Netherlands)
Cardiorespiratory fitness and risk of dementia: a longitudinal cohort study.
Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Introduction: Our main aim was to explore and elucidate whether metabolic equivalents of task (METs), as a measure of cardiorespiratory fitness (CRF), was associated with dementia. Method: A symptom-limited bicycle standard exercise test was performed in 4030 patients with no cardiovascular events. Dementia was classified according to International Classification of Diseases, Ninth and Tenth Revision codes. One MET corresponds to an oxygen uptake of 3.5 mL/kg/min. Results: During a median follow-up of 26.5 years, 104 cases of dementia occurred. In a fully adjusted model subjects with CRF of >9 METS had a 53% (hazard ratio (HR) 0.47, 95% CI (0.22, 0.99), p = 0.048) decreased risk of incidencec dementia compared to those CRF <6 METS. Discussion: Exercise training is an important modifiable factor that improves CRF and may help in dementia risk.
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