ArticleAmerican journal of medicine open2026
Risk of a Dementia Diagnosis in Community-Dwelling Older Adults With Normal MMSE Scores in the United States.
Article in American journal of medicine open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Background: The Mini-Mental State Examination (MMSE) is commonly used in clinical and research settings to assess cognitive function and scores 27-30 are considered normal. Whether individuals with lower MMSE scores within this normal range are at increased risk for Alzheimer's disease and related dementias (ADRD) remains unclear. We sought to examine this question in the current study. Methods: In the Cardiovascular Health Study (CHS), 4433 community-dwelling adults ≥ 65 years had MMSE 27-30: MMSE-30 ( Results: Individuals with MMSE-30, MMSE-29, MMSE-28, and MMSE-27 had mean ages of 71.1, 71.9, 72.6, and 73.4 years, and mean ADL impairment scores of 0.06, 0.08, 0.12 and 0.16, respectively (both Conclusions: These findings suggest that among community-dwelling older adults with normal MMSE, lower scores were associated with impaired ADL and significant, independent, and incrementally higher risk of ADRD.
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