ArticleJournal of conservative dentistry and endodontics2026
Dentin-preserving properties of cymbopogon nardus extract as a herbal endodontic irrigant against
Article in Journal of conservative dentistry and endodontics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Background: Enterococcus faecalis is a persistent endodontic pathogen that can survive conventional irrigation protocols. Herbal irrigants that combine antimicrobial efficacy with dentin preservation are therefore required in conservative endodontic therapy. Materials and Methods: Ethanolic extracts of CN were prepared at concentrations of 1%-5% (w/v) and tested against E. faecalis (ATCC 29212). Chlorhexidine 2.5% and saline were used as positive and negative controls, respectively. Antibacterial activity, biofilm inhibition, and bacterial viability were quantitatively assessed using growth inhibition (620 nm), crystal violet biofilm assay (580 nm), and MTT assay (570 nm) at 24, 48, and 72 h. Standardized human dentin specimens were prepared by root canal instrumentation and irrigated in accordance with the experimental groups. Dentin surface morphology and mineral composition were evaluated using scanning electron microscopy (SEM)/EDS, while fourier transform infrared (FTIR) spectroscopy assessed mineral and organic matrix integrity. Data were analyzed using the one-way ANOVA with least significant difference Results: CN showed concentration- and time-dependent antibacterial and antibiofilm effects, with CN 5% demonstrating the highest activity at 72 h ( Conclusion: Ethanolic CN extract demonstrates strong
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