Evidence mapPaperPMID 42004913Full record

ArticleJournal of arrhythmia2026

Association Between Bradyarrhythmia Requiring Permanent Pacemaker Implantation and Epicardial Adipose Tissue in Elderly Patients.

Shunsuke Tomomori, Keita Kimura, Naoya Hironobe, Kiho Itakura, Youji Urabe, Toshiharu Oka, Naoya Mitsuba, Yukihiro Fukuda, Hironori Ueda, Yukiko Nakano

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shunsuke TomomoriDepartment of Cardiology Hiroshima Prefectural Hospital Hiroshima Japan.
Keita KimuraDepartment of Cardiology Hiroshima Prefectural Hospital Hiroshima Japan.
Naoya HironobeDepartment of Cardiology Hiroshima Prefectural Hospital Hiroshima Japan.
Kiho ItakuraDepartment of Cardiology Hiroshima Prefectural Hospital Hiroshima Japan.
Youji UrabeDepartment of Cardiology Hiroshima Prefectural Hospital Hiroshima Japan.
Toshiharu OkaDepartment of Cardiology Hiroshima Prefectural Hospital Hiroshima Japan.
Naoya MitsubaDepartment of Cardiology Hiroshima Prefectural Hospital Hiroshima Japan.
Yukihiro FukudaDepartment of Cardiology Hiroshima Prefectural Hospital Hiroshima Japan.
Hironori UedaDepartment of Cardiology Hiroshima Prefectural Hospital Hiroshima Japan.
Yukiko NakanoDepartment of Cardiovascular Medicine Hiroshima University Graduate School of Biomedical and Health Sciences Hiroshima Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Aging is one of the most significant risk factors for sinus node (SN) and atrioventricular node (AVN) dysfunction. Epicardial adipose tissue (EAT) is reported to promote myocardial fibrosis and influence intracardiac conduction through the release of inflammatory cytokines and direct tissue infiltration. The SN and AVN are in contact with EAT, which may affect the SN function and AVN conduction. The purpose of this study was to examine the association between bradyarrhythmia and EAT. Methods: We enrolled 103 patients with bradyarrhythmia requiring permanent pacemaker (PM) implantations and 105 patients who underwent catheter ablation of paroxysmal supraventricular tachycardia in our hospital as a control (all patients were over 65 years old) and analyzed the preoperative echocardiograms retrospectively and measured the EAT thickness. We compared the EAT thickness between the PM group and control. Results: There were 38 (36.9%) PM group patients with sick sinus syndrome and 65 (63.1%) with advanced atrioventricular block. The EAT was significantly thicker in the PM group than control (PM group 4.6 ± 1.2 mm vs. control 3.6 ± 1.3 mm, Conclusions: The EAT thickness was associated with bradyarrhythmia requiring permanent PM implantation and may become a risk factor for SN and AVN dysfunction in elderly people.

Indexed as

bradyarrhythmiaepicardial adipose tissuepacemaker

Identifiers

PMID42004913
PMCPMC13084190

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.