Evidence map›Paper›PMID 42005232›Full record

ReviewCureus2026

What to Look for in Red Light Therapy: A Product Guide Backed by Science.

Colby V Spongberg, Emily R Stack, Caroline Aprigliano, Daniela Grinis, Stephanie Sawicki, Michelle Elway

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Colby V SpongbergCollege of Medicine, Touro College of Osteopathic Medicine, Great Falls, USA.
Emily R StackCollege of Medicine, William Carey University College of Osteopathic Medicine, Hattiesburg, USA.
Caroline ApriglianoCollege of Medicine, Touro College of Osteopathic Medicine, Great Falls, USA.
Daniela GrinisCollege of Medicine, Touro College of Osteopathic Medicine, Great Falls, USA.
Stephanie SawickiCollege of Medicine, Touro College of Osteopathic Medicine, Great Falls, USA.
Michelle ElwayCollege of Osteopathic Medicine, Touro College of Osteopathic Medicine, Great Falls, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photobiomodulation (PBM) is an emerging non-invasive modality for skin rejuvenation that utilizes specific wavelengths of red and near-infrared (NIR) light to enhance mitochondrial function and promote cellular repair. The downstream effects of mitochondrial efficiency improve wound healing, pain relief, and aesthetic outcomes. Although early research has encouraging results, the exact pathways by which PBM exerts its effects are still under investigation. PBM is known by other names, including red light therapy and low-level light therapy. Consumer devices are available in many forms, such as masks, wands, hand-held panels, laser caps, and full-body systems. With the rise in popularity, understanding the underlying biological mechanisms of PBM is becoming increasingly important. Equally critical is the selection of a product that has undergone the necessary U.S. Food and Drug Administration (FDA) channels, ensuring the device is backed by scientific evidence. This paper specifically serves as a guide for selecting safe, evidence-based PBM mask devices. This review discusses the mitochondrial and enzymatic mechanisms of action while providing a comprehensive literature review of available mask products that are both FDA-cleared and supported by scientific papers.

Indexed as

atp productioncollagen synthesiscytochrome c oxidasemitochondrial functionnear-infrared lightnitric oxidephotobiomodulationreactive oxygen speciesred light therapyskin rejuvenation

Identifiers

PMID42005232
PMCPMC13085462

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.