Evidence map›Paper›PMID 42005241›Full record

ReviewCureus2026

Postbiotics in Dermatology: A Literature Review of Emerging Topical Therapies for Acne, Rosacea, and Eczema.

Julio César Flores Rodríguez, María José Morán Ortega, Alison Cristina Jimenez Ordoñez, Aylin Kerime Rojas López, Mariana Castañeda Leyva, Haizel Valencia Romero

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Julio César Flores RodríguezAesthetic and Regenerative Medicine, Sociedad Mexicana de Investigación en Medicina Estética (SOMIME), Monterrey, MEX.
María José Morán OrtegaAesthetic and Regenerative Medicine, Consultorio Particular Dra. María José Morán, Valle del Cauca, COL.
Alison Cristina Jimenez OrdoñezEmergency, Hospital San Rafael de Alajuela, San José, CRI.
Aylin Kerime Rojas LópezInternal Medicine, Hospital General de Culiacán "Dr. Bernardo J. Gastélum", Culiacán, MEX.
Mariana Castañeda LeyvaAesthetic and Regenerative Medicine, Sociedad Mexicana de Investigación en Medicina Estética (SOMIME), Monterrey, MEX.
Haizel Valencia RomeroRegenerative Medicine, Universidad Nacional Autónoma de México, Mexico City, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postbiotics, defined as non-viable microbial cells and their metabolites, have emerged as topical therapies for inflammatory dermatoses and provide more clinical benefits than live postbiotics by eliminating infection risk and stability. This literature review aims to generalise existing knowledge about the effectiveness and mechanisms of action of first-line topical postbiotic treatments for acne, rosacea, and eczema. Search terms included "postbiotics" and keywords that represented the dermatological conditions of interest. Thematic synthesis was performed on the systematically extracted data. After screening, 16 studies were included in the review. Postbiotic preparations showed significant reductions in Scoring Atopic Dermatitis (SCORAD) and pruritus and improved barrier function in the skin, as well as longer remissions (p < 0.001). In acne vulgaris, postbiotics decreased inflammatory lesions by 50% to 70%, suppressed sebum secretion (42% to 72%), and stopped the growth of

Indexed as

acne vulgarisatopic dermatitiseczemapostbioticsrosaceaskin microbiometopical therapy

Identifiers

PMID42005241
PMCPMC13089085

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.