Evidence map›Paper›PMID 42005484›Full record

ArticleJournal of pharmacy & bioallied sciences

Investigating the Application of Stem Cell Therapy for Regenerating Dentin in Patients with Traumatic Dental Injuries: A Database Research.

Shilpa Shetty, Khushboo Changani, Anjum Patan, Pratik Agrawal, Anil M Managutti, Rahul Tiwari

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shilpa ShettyDepartment of Conservative Dentistry and Endodontics, Tatyasaheb Kore Dental College and Research Centre, New Pargaon, Kolhapur, Maharashtra, India.
Khushboo ChanganiDepartment of Oral and Maxillofacial Surgery, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, Gujarat, India.
Anjum PatanBDS, Mamata Dental College, Khammam, Telangana, India.
Pratik AgrawalDepartment of Conservative Dentistry and Endodontics, Kalinga Institute of Dental Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha, India.
Anil M ManaguttiDepartment of Oral and Maxillofacial Surgery, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, Gujarat, India.
Rahul TiwariDepartment of Oral and Maxillofacial Surgery, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, Gujarat, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Traumatic dental injuries (TDIs) often compromise the dentin-pulp complex, necessitating innovative therapeutic approaches. Stem cell therapy has emerged as a promising solution for regenerative endodontics. Objective: This research investigates the application of stem cell therapy in regenerating dentin for patients with TDIs by using a retrospective analysis of clinical outcomes. Methods: A retrospective data analysis was performed on 120 cases involving TDIs treated with stem cell-based interventions. Key parameters included patient demographics, clinical outcomes, and histological findings. Statistical significance was assessed using a Results: Significant improvement in dentin regeneration was observed in 85% of cases treated with stem cell therapy. Histological findings confirmed the formation of tubular dentin in 75% of cases. Younger patients exhibited superior outcomes compared to older cohorts. Conclusion: Stem cell therapy demonstrates significant potential for regenerating dentin in TDIs. Future studies should explore long-term outcomes and optimization of protocols.

Indexed as

Clinical outcomesdentin regenerationregenerative endodonticsstem cell therapytraumatic dental injuries

Identifiers

PMID42005484
PMCPMC13086403

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.