Evidence map›Paper›PMID 42005782›Full record

ArticleCurrent developments in nutrition2026

Pilot Trial of

Yonatan Y Cariño-Cervantes, Martha Guevara-Cruz, Omar Noel Medina-Campos, José Pedraza-Chaverri, Lilia Castillo-Martínez, Victoria Ramírez, Sara Montaño-Benavidez, Alexandro J Martagón, Paloma Almeda-Valdes, Luis Cisneros-Zevallos and 2 more

Abstract read
In one paragraph

Article in Current developments in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yonatan Y Cariño-CervantesDepartamento de Nutrición Animal Dr. Fernando Pérez-Gil Romo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.
Martha Guevara-CruzDepartamento de Fisiología de la Nutrición, Instituto Nacional de Nutrición y Ciencias Médicas Salvador Zubirán, Ciudad de México, México.
Omar Noel Medina-CamposDepartamento de Biología, Facultad de Química, Universidad Nacional Autónoma de México (UNAM), CDMX, México.
José Pedraza-ChaverriDepartamento de Biología, Facultad de Química, Universidad Nacional Autónoma de México (UNAM), CDMX, México.
Lilia Castillo-MartínezServicio de Nutriología Clínica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.
Victoria RamírezDepartamento de Nutrición Animal Dr. Fernando Pérez-Gil Romo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.
Sara Montaño-BenavidezDepartamento de Nutrición Animal Dr. Fernando Pérez-Gil Romo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.
Alexandro J MartagónUnidad de Investigación de Enfermedades Metabólicas, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.
Paloma Almeda-ValdesDepartamento de Endocrinología y Metabolismo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.
Luis Cisneros-ZevallosDepartment of Horticultural Sciences, Texas A&M University, College Station, TX, United States.
Carlos A Aguilar-SalinasDirección de Investigación, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.
Claudia Delgadillo-PugaDepartamento de Nutrición Animal Dr. Fernando Pérez-Gil Romo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Medicinal plants contain bioactive compounds with potential benefits for metabolic regulation, including glucose homeostasis. Objectives: This study aimed to evaluate the feasibility, safety, and acute metabolic effects of a polyphenol-rich extract from VF pods in healthy adults, with emphasis on glycemic regulation and incretin hormone responses. Methods: A single-blind, randomized, controlled pilot trial was conducted in 60 healthy volunteers (BMI 18.5-24.9 kg/m Results: VF extract was well tolerated, with no adverse clinical events or biochemical changes in liver and kidney function. Glycemic reduction during OGTT ( Conclusions: A single oral dose of VF polyphenol extract was safe for healthy individuals. In a predefined subsample (

Indexed as

glucagon-like peptide-1glucose-dependent insulinotropic polypeptideglucose tolerancesafetytranslational researchVachellia farnesiana

Identifiers

PMID42005782
PMCPMC13089003

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.