Evidence map›Paper›PMID 42006292›Full record

ArticleiScience2026

Hypoxia-induced metabolic and apoptotic reprogramming enhances immunomodulation in Wharton's jelly mesenchymal stem cells.

Mohini Mendiratta, Meenakshi Mendiratta, Sujata Mohanty, Hridayesh Prakash, Lakshay Malhotra, Sandeep Rai, Vijaya Sarangathem, Sabyasachi Bandyopadhyay, GuruRao Hariprasad, Ritu Gupta and 16 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Mohini MendirattaDepartment of Medical Oncology, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi 110029, India.
Meenakshi MendirattaStem Cell Facility (DBT-Centre of Excellence for Stem Cell Research), All India Institute of Medical Sciences, New Delhi 110029, India.
Sujata MohantyStem Cell Facility (DBT-Centre of Excellence for Stem Cell Research), All India Institute of Medical Sciences, New Delhi 110029, India.
Hridayesh PrakashAmity Centre for Translational Research, Amity University, Sector 125, Noida 201313, India.
Lakshay MalhotraDepartment of Biochemistry, Sri Venkateswara College, University of Delhi, New Delhi 110021, India.
Sandeep RaiLaboratory Oncology Unit, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi 110029, India.
Vijaya SarangathemDepartment of Biochemistry and Cell Biology, Cell & Matrix Research Institute, Kyungpook National University, School of Medicine, Daegu 41944, Republic of Korea.
Sabyasachi BandyopadhyayProteomics Sub-facility, Centralized Core Research Facility, All India Institute of Medical Sciences, New Delhi 110029, India.
GuruRao HariprasadDepartment of Biophysics, All India Institute of Medical Sciences, New Delhi 110029, India.
Ritu GuptaLaboratory Oncology Unit, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi 110029, India.
Sameer BakhshiDepartment of Medical Oncology, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi 110029, India.
Vatsla DadhwalDepartment of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi 110029, India.
Deepam PushpamDepartment of Medical Oncology, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi 110029, India.
Mukul AggarwalDepartment of Hematology, All India Institute of Medical Sciences, New Delhi 110029, India.
Aditya Kumar GuptaDepartment of Pediatric Oncology, All India Institute of Medical Sciences, New Delhi 110029, India.
Prabhat Singh MalikDepartment of Medical Oncology, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi 110029, India.
Raja PramanikDepartment of Medical Oncology, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi 110029, India.
Manoranjan MahapatraDepartment of Hematology, All India Institute of Medical Sciences, New Delhi 110029, India.
Tulika SethDepartment of Hematology, All India Institute of Medical Sciences, New Delhi 110029, India.
Rishi DhawanDepartment of Hematology, All India Institute of Medical Sciences, New Delhi 110029, India.
Baibaswata NayakDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi 110029, India.
Thoudam Debraj SinghDepartment of Medical Oncology, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi 110029, India.
Sachin KumarDepartment of Medical Oncology, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi 110029, India.
Riyaz Ahmed MirDepartment of Biochemistry, All India Institute of Medical Sciences, New Delhi 110029, India.
Surender Kumar SharawatDepartment of Medical Oncology, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi 110029, India.
Ranjit Kumar SahooDepartment of Medical Oncology, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi 110029, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) possess immunomodulatory properties that can be harnessed for treating acute graft-versus-host disease (aGVHD). In this study, we compared bone marrow (BM) and Wharton's jelly (WJ)-derived MSCs and investigated how hypoxia preconditioning (1% O

Indexed as

cell biologyimmunologystem cells research

Identifiers

PMID42006292
PMCPMC13089076

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.