Evidence map›Paper›PMID 42006312›Full record

ArticleiScience2026

Repurposing drugs for treating the neurobehavioral manifestations of PTEN hamartoma tumor syndrome.

Tim Fieblinger, Judith Rudolph, Kerstin Müller, Petra Friess, Nicole Weigelt, Christina Thiede, Simone Modolo, Denise Federico, Malik Majandinow, Federico Tinarelli and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Tim FieblingerEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Judith RudolphEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Kerstin MüllerEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Petra FriessEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Nicole WeigeltEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Christina ThiedeEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Simone ModoloEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Denise FedericoEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Malik MajandinowEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Federico TinarelliEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Vivian J A CostantiniEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Pier P MarreseEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Annalisa MercuriEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Nikisha CartyEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Ana Christina GomesPTEN Research, 4th Floor, St James House, St James Square, Cheltenham, Gloucestershire GL50 3PR, UK.
Maria A WhiteheadMaria Whitehead Consulting OY, 00250 Helsinki, Finland.
Philip A GerrardEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Chrisovalantis PapadopoulosEvotec SE, Essener Bogen 7, 22419 Hamburg, Germany.
Paul ElvinPTEN Research, 4th Floor, St James House, St James Square, Cheltenham, Gloucestershire GL50 3PR, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PTEN hamartoma tumor syndrome (PHTS) is caused by mutation of

Indexed as

Cancer systems biologyMolecular biologyPharmaceutical science

Identifiers

PMID42006312
PMCPMC13091523

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.