ArticleJournal of bone oncology2026
Health-related quality of life and physical activity in children with Multiple Osteochondromas.
Article in Journal of bone oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Fatigue and pain in children with multiple osteochondromas: a cross-sectional study.Orphanet journal of rare diseases · 2026Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To evaluate health-related quality of life (HRQOL) and physical activity level (PAL) in children and adolescents with Multiple Osteochondromas (MO) and to identify factors associated with these outcomes. Study design: Cross-sectional survey of Dutch patients aged 4-18 years recruited through the national MO expertise center and the patient association. Validated, age-specific questionnaires assessed HRQOL (TAP/TAC/TAAQOL), PAL (Baecke), pain, functional disability, and psychosocial and sociodemographic variables. Multiple linear regression, guided by the International Classification of Functioning framework, examined associated variables with the mental and physical HRQOL components and with PAL. Results: A total of 134 participants (53% male; mean age ± SD, 11.4 ± 3.7 years) completed the survey. Compared with population norms, patients with MO scored significantly lower on physical HRQOL but not consistently lower on mental HRQOL. Significant gender differences emerged in specific HRQOL domains across multiple age groups. Mean PAL was also reduced (7.35 ± 1.01, p < 0.001) compared with healthy peers. Physical HRQOL (R Conclusions: The pediatric MO population reports significantly lower physical HRQOL and PAL, but not consistently lower mental HRQOL than healthy peers. Specific gender differences were observed across multiple domains. The associations identified in this study call for a multidisciplinary approach to MO management that emphasizes pain control, functional rehabilitation, and psychosocial support.
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