Evidence mapPaperPMID 42006456Full record

ArticleMindfulness2026

"Noticing the Way that I'm Noticing Pain": A Qualitative Analysis of Therapeutic Progression in Mindfulness-Oriented Recovery Enhancement for Patients with Lumbosacral Radicular Pain.

Ryan S Wexler, Wade Balsamo, Devon J Fox, Danielle ZuZero, Anand Parikshak, Sophia Kwin, Jillian Ramirez, Austin R Thompson, Hans L Carlson, Thomas Kern and 5 more

Abstract read
In one paragraph

Article in Mindfulness, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ryan S WexlerHelfgott Research Institute, National University of Natural Medicine, Portland, United States.
Wade BalsamoHelfgott Research Institute, National University of Natural Medicine, Portland, United States.
Devon J FoxHelfgott Research Institute, National University of Natural Medicine, Portland, United States.
Danielle ZuZeroHelfgott Research Institute, National University of Natural Medicine, Portland, United States.
Anand ParikshakHelfgott Research Institute, National University of Natural Medicine, Portland, United States.
Sophia KwinHelfgott Research Institute, National University of Natural Medicine, Portland, United States.
Jillian RamirezHelfgott Research Institute, National University of Natural Medicine, Portland, United States.
Austin R ThompsonDepartment of Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, United States.
Hans L CarlsonDepartment of Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, United States.
Thomas KernComprehensive Pain Center, Oregon Health & Science University, Portland, United States.
Scott D MistHelfgott Research Institute, National University of Natural Medicine, Portland, United States.
Ryan BradleyHelfgott Research Institute, National University of Natural Medicine, Portland, United States.
Heather ZwickeyHelfgott Research Institute, National University of Natural Medicine, Portland, United States.
Courtney K PickworthHelfgott Research Institute, National University of Natural Medicine, Portland, United States.
Eric L GarlandDepartment of Psychiatry, University of California, San Diego, San Diego, United States.

Funding

University of Michigan (UM) HEAL Initiative National K12 Clinical Pain Career Development Program (UM-HCPDP)K12NS130673 · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2025 to 2025
$3.1M
NINDS NIH HHS K12 NS130673
6 · The paper itself

Abstract

Objectives: Mindfulness-Oriented Recovery Enhancement (MORE) aims to foster adaptive attention and pain reappraisal. While research has demonstrated MORE's efficacy, the progression through which participants modify their relationship to pain remains unclear. To understand this process, we conducted a qualitative study with data from a clinical trial of MORE for patients with lumbosacral radicular pain (LRP). Method: Thirty session recordings from MORE were coded. Using thematic analysis, we examined therapeutic processing sessions to understand how participants learned and applied mindfulness to pain. Analysis focused on dialogue resulting from MORE's model of processing, Phenomenology, Utilization, Reframing, Education, Reinforcement (PURER). Results: Four stages and one barrier were identified: (1) Pain Vigilance and Attention Dysregulation, (2) Attention Regulation and its application to Experiential Avoidance, (3) Metacognitive Awareness, and (4) Pain Reappraisal. In addition, some participants engaged in experiential avoidance by using their newfound attention skills to avoid their pain experience. PURER emerged as crucial in facilitating adaptive pain engagement. Conclusions: The four-stage progression pattern identified here - the Vigilance-Avoidance Metacognition-Reappraisal (VA-MR) framework - may help clinicians anticipate challenges in mindfulness training. This study illuminates how MORE participants develop an adaptive relationship with chronic pain, and while attention regulation skills are necessary, they may initially be used for avoidance. Therapeutic benefit appears to require guidance through these stages by a skilled therapist who can navigate initial avoidance tendencies. These findings offer an actionable model for assessing progress and tailoring MBIs to enhance therapeutic outcomes.

Indexed as

Back painLongitudinal analysisMindfulnessNon-pharmacologic managementQualitative analysisRadiculopathy

Identifiers

PMID42006456
PMCPMC13083439

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.