ReviewMaterials today. Bio2026
Illuminating the metabolic sink: Optical probes for in vivo thermogenic fat imaging.
Review in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As a metabolic sink, thermogenic fat plays a pivotal role in the pathogenesis of metabolic diseases, yet current techniques for assessing its location and activity in vivo face challenges, such as high costs and operational complexity. Optical imaging, encompassing label-free and labeled modalities, offers a relatively cost-effective and straightforward alternative. In comparison with the label-free modality, labeled optical imaging stands out for its superior performance, which is attributed to the utilization of advanced optical probes with enhanced specificity and sensitivity. Despite significant advancements in optical probes for thermogenic fat detection, systematic compilations related to these studies remain scarce. Hence, this review concentrates on four typical categories of optical probes and expounds their physicochemical properties, imaging benefits, and applications in thermogenic fat assessment. Their imaging targets, design strategies, translational challenges, and perspectives are also discussed. As a reference resource, this review will facilitate the development of more reliable and safer optical probes targeting thermogenic fat, thereby assisting in precise theranostics for metabolic diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.