Evidence map›Paper›PMID 42006919›Full record

ReviewClinical neurophysiology practice2026

Home use of low-intensity transcranial electrical stimulation in clinical practice: an IFCN handbook chapter.

Perianen Ramasawmy, Marom Bikson, Jerome Brunelin, Kyle Donnery, Alexander Hunold, Jean-Pascal Lefaucheur, Marine Mondino, Teresa Schuhmann, Antonio Oliviero, Andrea Antal

Abstract readReview
In one paragraph

Review in Clinical neurophysiology practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Perianen RamasawmyNon-Invasive Brain Stimulation Lab, Department of Neurology, University Medical Center Göttingen, Göttingen, Germany.
Marom BiksonDepartment of Biomedical Engineering, The City College of New York, NY, United States.
Jerome BrunelinUniversité Claude Bernard Lyon 1, CNRS, INSERM, Centre de Recherche en Neurosciences de Lyon CRNL U1028, UMR5292, PsyR2 Team, Bron, France.
Kyle DonneryDepartment of Biomedical Engineering, The City College of New York, NY, United States.
Alexander HunoldInstitute of Biomedical Engineering and Informatics, TU Ilmenau, Ilmenau, Germany.
Jean-Pascal LefaucheurUR4391 (ENT Team), Faculty of Health, Paris Est Créteil Université, Créteil, France.
Marine MondinoUniversité Claude Bernard Lyon 1, CNRS, INSERM, Centre de Recherche en Neurosciences de Lyon CRNL U1028, UMR5292, PsyR2 Team, Bron, France.
Teresa SchuhmannDepartment of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, the Netherlands.
Antonio OlivieroFENNSI Group, Hospital Nacional de Parapléjicos, SESCAM, Toledo, Spain.
Andrea AntalNon-Invasive Brain Stimulation Lab, Department of Neurology, University Medical Center Göttingen, Göttingen, Germany.

Funding

G-RISE: Graduate Research Initiative for Student Advancement at The City College of New YorkT32GM136499 · NIGMS · CITY COLLEGE OF NEW YORK · PI RUTH E. STARK · 2020 to 2026
$4.9M
NIGMS NIH HHS T32 GM136499
6 · The paper itself

Abstract

Non-invasive brain stimulation (NIBS) includes a growing set of techniques aimed at modulating brain activity without surgery or implants. Transcranial magnetic (TMS) and electrical stimulation (tES) are among the most established methods. tES delivers low-intensity current via scalp electrodes, offering a cheaper and portable option, especially for home-based use. Clinical evidence suggests that the effects of tES are cumulative with consecutive applications needed to achieve meaningful changes. The therapeutic application of the clinic-based tES usually involves a minimum of two weeks of daily visits to the clinical institute, which poses a large burden and stress on patients. Home-based tES, e.g. under remote supervision (RS-tES), following adequate training by trained professionals paves the path to increasing the accessibility of the technology to patients. In 2025, the US FDA approved the first home-based tDCS system for the treatment of "moderate to severe major depressive disorder in the current episode, either as monotherapy or as an adjunctive treatment, in patients 18 years and older who are not considered treatment refractory to medication. In this work, the latest knowledge related to home-use of tES is introduced, including the methodology, most frequent clinical applications, advances and limitations.

Identifiers

PMID42006919
PMCPMC13084587

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.