ReviewAmerican journal of translational research2026
Uterine microbiota dynamics and new therapeutic opportunities in gynecological diseases.
Review in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traditional view holds that the uterus is a sterile environment. However, with the increased development of molecular biology technologies, this classical theory has been re-examined. Increasing evidence shows that a low-biomass, uniquely structured microecosystem exists in the healthy uterus. Its composition and dynamic changes are crucial in maintaining endometrial homeostasis, regulating immune responses, and influencing embryo implantation. Uterine microecological imbalance is associated with different gynecological diseases, such as chronic endometritis, endometriosis, and uterine-related tumors. This paper systematically reviews the compositional features of the uterine microecology and the dynamic changes in bacterial communities, as well as summarizes the evidence linking these changes to major gynecological diseases. This work examines current treatment and intervention strategies including antibiotics, probiotics, uterine cavity colonization, and fecal microbiota transplantation, and discusses their potential clinical value and methodological challenges. A deeper investigation of the relationship between uterine microecology and gynecological diseases is expected to provide new biomarkers and therapeutic targets for the precise diagnosis and treatment of gynecological disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.