ArticleVeterinary and animal science2026
The bovine mammosphere-derived epithelial cell secretome inhibits bacterial growth in vitro and contains peptidoglycan recognition protein 1.
Article in Veterinary and animal science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Bovine mastitis, caused by bacterial infection of the mammary gland, leads to significant economic losses for the dairy industry because of decreased milk quality and yield. Mastitis is typically treated with conventional antibiotics (ABX) that clear bacteria, but do not address the milk loss associated with infection. Milk from cows being treated with ABX must be discarded leading to acute milk loss, and ABX do not heal milk-producing tissues that are damaged because of infection, leading to a permanent reduction in milk production when compared to pre-mastitis levels. The bovine mammosphere-derived epithelial cell (MDEC) secretome, consisting of all bioactive factors secreted by the cells, contains molecules that directly and indirectly promote tissue repair. This current study shows that the MDEC secretome also inhibits the growth of mastitis-causing bacteria
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