Evidence map›Paper›PMID 42008135›Full record

ArticleLangenbeck's archives of surgery2026

Artificial intelligence for surgical management of benign esophageal disease: scoping review and evidence mapping.

Alberto Aiolfi, Quan Wang, Pietro Mascagni, Davide Bona, Nicola Leone, Luigi Bonavina

Abstract readScoping Review
In one paragraph

Article in Langenbeck's archives of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alberto AiolfiDepartment of Biomedical Sciences for Health, I.R.C.C.S. Ospedale Galeazzi - Sant'Ambrogio, Division of General Surgery, University of Milan, Milan, Italy.
Quan WangDepartment of Pharmacy, Health and Nutrition Sciences, Azienda Ospedaliera di Cosenza, Division of General and Foregut Surgery, University of Calabria (UNICAL), Rende, (Cosenza), Italy.
Pietro MascagniBioimage Analysis Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italia.
Davide BonaDepartment of Biomedical Sciences for Health, I.R.C.C.S. Ospedale Galeazzi - Sant'Ambrogio, Division of General Surgery, University of Milan, Milan, Italy.
Nicola LeoneArtificial Intelligence Laboratory, Department of Mathematics and Computer Science, University of Calabria (UNICAL), Rende, (Cosenza), Italy.
Luigi BonavinaDepartment of Pharmacy, Health and Nutrition Sciences, Azienda Ospedaliera di Cosenza, Division of General and Foregut Surgery, University of Calabria (UNICAL), Rende, (Cosenza), Italy. luigi.bonavina@unical.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial intelligence (AI) has seen considerable growth mainly in surgical oncology, with current applications primarily centered on cancer diagnosis, staging, treatment planning, and outcomes prediction. Aim of the present scoping review was to describe the actual evidence and future perspectives of AI-application in the field of benign esophageal diseases.

methodsThis scoping review summarizes current evidence on AI utilization in the diagnosis and surgical management of esophageal benign disease such as achalasia, Barrett’s esophagus, gastroesophageal reflux disease (GERD), hiatus hernia (HH), and Zenker diverticulum. PubMed, Scopus, Web of Science, Cochrane Library, and Google Scholar databases were searched until November 2025.

resultsOverall, 37 studies published were included. The integration of AI within the surgical protocols of tertiary referral centers may offer the potential to enhance multidisciplinary decision-making, provide intraoperative assistance, and lead to improved patient outcomes by personalizing treatment of reflux disease, motility disorders and esophageal diverticula. Also, there is an urgent need of responsible AI development and implementation to support surgical education through objective skill assessment, simulation-based training, and competency evaluation. Machine learning, deep learning and hybrid models are still underexplored. Since continuous learning and system adaptability are crucial in healthcare, collaborative efforts to develop robust and validated patient-centered AI tools that align with real-world surgical workflow have the potential to uncover hidden trends and to deliver reliable predictions. Ultimately, AI applications within esophageal surgery must adhere to the ethical standards that define surgical practice: safety, transparency, accountability, equity, and dedication to patient welfare. By ensuring that innovation remains aligned with these foundational principles, AI can serve to elevate both the precision of surgical care and the preparation of future surgeons.

conclusionsAI can improve every stage of surgical care for benign esophageal disease, from diagnosis to postoperative management. It may also help standardize surgeon training and speed up learning for laparoscopic and robotic procedures. Realizing AI’s full benefits will require strong research, ethical practices, and thorough surgeon education.

Indexed as

Artificial IntelligenceEsophageal DiseasesHumansArtificial intelligenceDeep learningEsophagusLaparoscopic surgeryLower esophageal sphincterMachine learningRobotic surgery

Identifiers

PMID42008135
PMCPMC13222892

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.