Evidence map›Paper›PMID 42008849›Full record

ReviewRedox biology2026

The zinc-nitric oxide axis in acute brain injury: Convergent oxidative-nitrative stress, peroxynitrite signaling, and therapeutic targets.

Hyun Wook Yang, Min Kyu Park, Hyun Ho Jeong, Sang Won Suh

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Redox biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hyun Wook YangDepartment of Physiology, Hallym University, College of Medicine, Chuncheon, Republic of Korea.
Min Kyu ParkDepartment of Physiology, Hallym University, College of Medicine, Chuncheon, Republic of Korea.
Hyun Ho JeongDepartment of Physiology, Hallym University, College of Medicine, Chuncheon, Republic of Korea.
Sang Won SuhDepartment of Physiology, Hallym University, College of Medicine, Chuncheon, Republic of Korea; Hallym Institute of Epilepsy Research, Republic of Korea. Electronic address: swsuh@hallym.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute brain injuries are characterized by secondary cascades driven by oxidative and nitrative stress. While the roles of excitotoxicity and neuroinflammation in acute brain injury are well recognized, emerging evidence indicates that the interaction between dysregulated zinc (Zn

Indexed as

Brain InjuriesNitric OxideOxidative StressPeroxynitrous AcidZincAnimalsHumansMitochondriaOxidation-ReductionReactive Oxygen SpeciesSignal TransductionNitric OxidePeroxynitrous AcidReactive Oxygen SpeciesZincMitochondrial dysfunctionNeuroinflammationOxidative and nitrative stressPeroxynitriteZinc dyshomeostasisZinc–nitric oxide axis

Identifiers

PMID42008849
PMCPMC13094650

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.