ArticleKlinische Monatsblatter fur Augenheilkunde2026
Optical Coherence Tomography Angiography in Patients with Systemic Lupus Erythematodes.
Article in Klinische Monatsblatter fur Augenheilkunde, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abstract: PURPOSE: Systemic lupus erythematodes (SLE) is a connective tissue disorder with multisystem involvement that leads to an immune complex-mediated angiopathy with deposition in the endothelial cells of small blood vessels. The purpose of this study was to analyse the retinal vasculature, using optical coherence tomography angiography (OCTA) in patients with SLE. Abstract:
methodsThis is a single-institution cross-sectional study. Macular OCTA images (6 × 6 and 3 × 3 mm) were acquired in healthy controls (HC) and patients with SLE. En face images of the retinal vasculature were generated from the superficial and deep capillary plexus (SCP/DCP). The vessel density (VD) and vessel length density (VLD) were measured by previously published methods. VD was assessed as the ratio of the retinal area occupied by vessels. VLD was measured as the total length of the skeletonised vessels using 1-pixel center line extraction of the blood vessels. Quantitative analysis of the VD, VLD, and the foveal avascular zone FAZ was performed. Abstract:
results25 patients (49 eyes) with clinically established SLE and 80 eyes of 66 healthy controls (HC) were included. Among the patients with SLE, the mean age was 41.47 (± 9.27 SD) years with 92% female patients and in the healthy individuals 37.1 years (± 14.33 SD) with 56% female patients. The mean VD of the SCP in the SLE-group was 0.34 ± 0.02, the VLD of SCP was 17.08 ± 1.58 mm Abstract:
conclusionsSwept-source OCTA of the microcirculation in eyes of patients with SLE can be used to quantitatively demonstrate a reduction in VD in SCP and DCP and VLD in SCP compared to healthy eyes. The reduction of the capillary network in the superficial and deep capillary plexus indicates an association with SLE disease status and future longitudinal studies may use these metrics to evaluate changes over time and its correlation to disease severity. Further studies are warranted to evaluate the relevance of these microvascular alterations in the setting of SLE and its correlation to disease severity.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.